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Cortexolone 17α-propionate ufa

mlingo:
4.50 kuchokera 5 kutengera 2 mavoti kasitomala
SKU: 19608-29-8. Category:

AASraw ili ndi kaphatikizidwe ndi kapangidwe kake kuchokera ku gramu mpaka kulemera kwa ufa wa Cortexolone 17α-propionate (19608-29-8), pansi pa lamulo la CGMP ndi dongosolo loyendetsa khalidwe labwino.

Mafotokozedwe Akatundu

Video ya Cortexolone 17A-propionate


Cortexolone 17α-propionate ufa Anthu oyambirira

Name: Cortexolone 17α-propionate ufa
CAS: 19608-29-8
Makhalidwe a Maselo: C24H34O5
Kulemera kwa maselo: 402.52
Melt Point:
Kusungirako nyengo: Kutentha kwa Chipinda
mtundu; Yoyera mpaka woyera-ufa ufa


Kortexolone 17α-propionate cycle

Mayina

CAS: 19608-29-8
Maina a Mankhwala: cortexolone-17α-propionate,
Maina Ena: CB-03-01, ufa wa Winlevi, ufa wa Breezula, 11-deoxycortisol 17α-propionate, Cortexolone 17α-propionate ufa

Ntchito ya Cortexolone 17α-propionate

Cortexolone 17A-propionate ndi yopangidwa ndi steroidal antiandrogen - makamaka, ndi antirogenous antagonist - yomwe ili pansi pa chitukuko cha Cassiopea ndi Intrepid Therapeutics kuti igwiritsidwe ntchito ngati mankhwala opatsirana pogwiritsa ntchito mankhwala a androgen kuphatikizapo acne vulgaris ndi aloroseki alopecia kupweteka kwa tsitsi).

Kodi mlingo wa Cortexolone 17α-propionate ndi chiani?

Cortexolone 17α-propionate 1% kirimu, antiandrogeni yatsopano yatsopano ya mankhwala opangira ma acne vulgaris. Woyendetsa ndege wotsutsana, wophunzira mobwerezabwereza poyerekezera ndi placebo ndi tretinoin 0 · 05% kirimu.

MALANGIZO

Acne vulgaris ndi matenda a chipangizo chokhalira pansi chomwe ma androgens amathandizira kuti chiyambire ndi kupitiriza. Kugwiritsa ntchito antiandrogens kotero kungakhale kotheka; Komabe, antiandrogens za ntchito zamagetsi sizimapezeka pamsika. Cortexolone 17α-propionate ndi watsopano wotsutsana ndi antiandrogen yomwe ingakhale yopindulitsa mu acne vulgaris.

ZOLINGA

Kufufuza mmene chitetezo ndi kapangidwe kake ka Cortexolone 17α-propionate 1% kirimu mu acne vulgaris poyerekeza ndi placebo ndi tretinoin 0 · 05% kirimu.

NJIRA

Amuna makumi asanu ndi awiri mphambu asanu ndi awiri omwe ali ndi zikopa za nkhope akuganiza kuti 2-3 malinga ndi kafukufuku wa Global Assessment (IGA) amatha kulandira zonona (n = 15), kapena Cortexolone 17A-propionate 1% kirimu (n = 30), kapena XTUM 0 · 05 % kirimu (n = 32) kamodzi pa tsiku pogona pa masabata a 8. Kugwiritsa ntchito kachipatala kunayesedwa masabata onse a 2 kuphatikizapo chiwerengero cha zilonda zowerengeka (TLC), kupweteka kwa zilonda zamtundu wambiri (ILC), chifuwa chachikulu cha acne (ASI) ndi IGA. Kuwonetsetsa chitetezo kunaphatikizapo malipiro am'derali, kuyesa ma laboratory, kufufuza thupi, zizindikiro zofunika ndi kujambula zochitika zovuta.

ZINTHU

Chumacho cha CB-03-01 chinali cholekerera bwino, ndipo chinali chabwino kwambiri kuposa malo a placebo okhudza TLC (P = 0 · 0017), ILC (P = 0 · 0134) ndi ASI (P = 0 · 0090), komanso ogwira ntchito kwambiri kuposa kufanana. Zomwe zinapangidwanso zinapangitsanso mwamsanga kufufuza kwa 50% pazigawo zonsezi. CB-03-01

MAFUNSO

Kafukufukuyu akuthandizira kugwiritsidwa ntchito kwa antiandrogens pamatenda a acne vulgaris. Cortexolone 17α-propionate 1% kirimu ikuwoneka ngati ikugwirizana ndi mbiri ya antiandrogen yoyenera yogwiritsira ntchito zamaganizo.

Mmene Cortexolone 17α-propionate imagwirira ntchito

Cortexolone 17--propionate (CAS 19608-29-8), kapena 11-deoxycortisol 17α-propionate, ndi mankhwala opangidwa ndi steroidal antiandrogen - makamaka, a antirogenal receptor antagonist - omwe akutsogoleredwa ndi Cassiopea ndi Intrepid Therapeutics kuti agwiritsidwe ntchito ngati mankhwala opatsirana chithandizo cha mkhalidwe wa androgen wodalirika kuphatikizapo acne vulgaris ndi alorocenia alopecia (kusowa tsitsi kwa tsitsi la amuna). Ndi C17A propionate ester ya 11-deoxycortisol (cortexolone); C17α esters ya 11-deoxycortisol anapeza mosayembekezereka kuti ali ndi antiandrogen, ndipo cortexolone 17α-propionate inasankhidwa kuti ipite patsogolo pogwiritsa ntchito mbiri yabwino ya mankhwala.

Mu makoswe, mankhwalawa akupezeka kuti ali ndi ntchito yowonongeka ya antiandrogen, koma osagwiritsidwa ntchito mosagwiritsa ntchito mankhwala ophera antiandrogen pamene akugwiritsidwa ntchito pogwiritsa ntchito jekeseni wa subcutaneous. Kuwonjezera apo, cortexolone 17α-propionate sizowonjezereka, posonyeza kuti imasankha mwachisawawa. Pogwiritsa ntchito mankhwala osokoneza bongo, mankhwalawa anali aakulu kuposa a progesterone, flutamide, ndi finasteride ndipo anali ofanana ndi a cyproterone acetate.

Mlandu woyendetsa galimoto ku 2011 wa amuna omwe amachititsa khungu la cortexolone 17α-propionate 1% kirimu cha acne anapeza kuti mankhwalawa amalekerera kwambiri ndipo amachepetsa kwambiri zizindikiro za acne. Komanso, mphamvu yake inali yaikulu kwambiri kuposa yowonjezereka, tretinoin 0.05% kirimu. Malingana ndi 2017, mankhwalawa ali mu gawo lachitatu la ma ARV chifukwa cha acne vulgaris ndi mayesero a chigawo chachiwiri cha mankhwala a alogenic androgenic alopecia.

chenjezo

Cortexolone 17A-proprionate, Breezula powder m'mapangidwe ake: banja loyamba la patent, likutha ku United States mu 2022 / 23 ndi ku 2022 kudziko lonse lapansi, likugwiritsira ntchito mankhwala pa kachipatala ka mankhwala a acne, alopecia ndi matenda ena; Banja lachiwiri lachivomerezo limaphatikiza mitundu yonse yodziwika ya crystalline ya API, zolemba zomwe zili ndi API yomweyo komanso ntchito zochiritsira zogwiritsa ntchito kuchipatala, AGA ndi matenda ena: Banja lachibadwidwe limeneli laperekedwa kale ku United States, Europe, Canada, Japan ndi mayiko ena, adzatha mu 2030 ku United States ndi 2028 kudziko lonse lapansi.Breatzula powder

Kortexolone 17A-propionate Uphungu wambiri

10grams yayamba.
Funso labwino kwambiri (mkati mwa 1kg) lingatumizedwe mu maola a 12 mutatha kulipira.
Kuti muyambe kukonzekera mukhoza kutumizidwa mu masiku a ntchito 3 mutatha kulipira.

Cortexolone 17A-propionate Maphikidwe a Powder Wofiira

Kuti mufunse Wotumikira Wathu Woimira Wathu (CSR) kuti mudziwe zambiri, kwa wanu reference.Winlevi ufa

Malonda a Cortexolone 17α-propionate

Kuti aperekedwe m'tsogolomu.

Kodi Cortexolone 17A-propionate Ali ndi Zotsatira Zonse

Cortexolone 17α-propionate ndi watsopano wa steroidal-ester, wotsutsana ndi antirogenal-antagonist, amene amapatsidwa ntchito zochepa zowonongeka, zomwe zikuwoneka ngati zoyenera kuti azisamalidwa ndi acne vulgaris. CB-03-01 imagwira ntchito pamtundu wa munthu ndi -rogen-receptor popanda kuletsa 5α-reductase pakhungu. Steroid imalowa mosavuta khungu la anthu ndipo imathamangitsidwa mwamsanga kuti imatulutsa kolera cortexolone yomwe ilibe njira zowonongeka. Chofunika kwambiri, kufikira lero, sichiwonetsere zotsatirapo zapansi kapena zowonongeka za steroid.


Momwe mungagule Kortexolone 17α-propionate ufa kuchokera ku AASraw

1.Kutiwuza ife ndi imelo yathu kafukufuku, kapena skype pa intanetiwoimira makasitomala (CSR).
2.Zotipatseni ife afunsidwa zambiri ndi adiresi yanu.
3.Our CSR idzakupatsani inu ndondomeko, nthawi yobwezera, nambala yotsatira, njira yobweretsera ndi tsiku lofika kufika (ETA).
4.Payment yachitidwa ndipo katunduyo adzatumizidwa mu maola a 12 (Kukonzekera mkati mwa 10kg).
5.Goods inalandira ndi kupereka ndemanga.


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COA

HNMR

Maphikidwe

Cortexolone 17A-propionate Maphikidwe a Powder Wofiira:

Kuti mufunse Wotumikira Wathu Woimira Wathu (CSR) kuti mudziwe zambiri, kwa wanu reference.Winlevi ufa

Mafotokozedwe ndi zolemba zamagulu

Mankhwala Operewera Amtima Otsatira Amtima: Cortexolone 17α-propionate powder (CB-03-01)

2 amakambirana kwa Cortexolone 17α-propionate ufa

  1. Dr. Patrick Young -

    Tidzakulankhulani ndi imelo.

  2. adavotera 4 kuchokera 5

    Vitali -

    Как сделать заказ?

  3. adavotera 5 kuchokera 5

    Aasraw -

    Cortexolone 17α-propionate ndi katswiri

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