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BMS-564929 ufa

mlingo:
5.00 kuchokera 5 kutengera 1 kasitomala mlingo
SKU: 627530-84-1. Category:

AASraw ili ndi kaphatikizidwe ndi kapangidwe kameneka kuchokera ku gramu mpaka kulemera kwa BMS-564929-627530), pansi pa lamulo la CGMP ndi dongosolo loyendetsa khalidwe labwino.

BMS-564929 ufa ndi kafukufuku wamakono ndipo androgen receptor modulator, yomwe ikupangidwa ndi Bristol-Myers Squibb kuti athe kuchiza zizindikiro za kuchepa kwa zaka zowonjezera zakale mu amuna ("andropause"). Zizindikiro izi zingakhale kuphatikizapo, kutayika kwa minofu ndi mphamvu, kuchepetsa mu libido ndi matenda otupa mafupa. Malingana ndi zomwe zapeza, BBMS-564929 ufa umawoneka ngati SARM yabwino ya anabolic

Mafotokozedwe Akatundu

BMS-564929 powder video


I.BMS-564929 ufa Anthu oyambirira:

Name: BMS-564929 ufa
CAS: 627530-84-1
Makhalidwe a Maselo: C14H12ClN3O3
Kulemera kwa maselo: 305.71638
Melt Point: 175-184 ° C
Kusungirako nyengo: Dry, mdima ndi 0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata) kapena -20 ° C kwa nthawi yaitali (miyezi mpaka zaka)
mtundu; White powder


BMS-564929 powder (627530-84-1) mukumanga thupi

BMS-564929 powder Maina

BMS-564929 ufa

Kugwiritsa ntchito kwambiri kwa BMS-564929 powder

BMS-564929 powder ndizamphamvu kwambiri, zamagetsi, zopanda thupi zomwe zimagwiritsa ntchito mitsempha yotchedwa androgen receptor (AR) modulator. BMS-564929 ufa ndi subnanomolar AR agonist mu vitro, imasankha kwambiri AR ndi ena steroid hommoni receptors, ndipo mawonetsero sagwirizana kwambiri ndi SHBG kapena aromatase. Maphunziro a mphuno m'matumbo aamuna amasonyeza kuti BMS-564929 ufa wofiira ndi wolimba kwambiri kuposa testosterone (T) pofuna kulimbikitsa kukula kwa mtembo wa nyama, ndipo mosiyana ndi T, amasankha kwambiri minofu ndi prostate.

BMS-564,929 ndi imodzi mwa mankhwalawa pakalipano m'mayesero oyambirira a anthu, omwe ndi agalist ochita bwino, amphamvu komanso osankhidwa ndi agonist a androgen receptors (Ki 2.1nM, 20x ntchito yosankha minofu ya prostate) komanso pa maphunziro a makoswe omwe anawonekera Kugonjetsa kumachepetsanso minofu ya minofu pakapita nthawi, ndipo pa mlingo waukulu kwambiri umakhala ndi minofu yambiri, osakhudzidwa kwambiri ndi minofu ya prostate. Komabe zimakhala zochepetsetsa kwambiri kulemera kwake kwa ma hormone, pokhala chodabwitsa 33x chophatikizapo testosterone, chomwe chingakhale vuto mwa munthu ntchito zachipatala.
BMS-564929 ufa wofiira umamangiriza bwino kwa receptor ya androgen osati kwa ena steroid receptors. BMS-564929 ufa sakhala ndi mgwirizano ndi SHBG ndipo siimabisa aromatase. Mayeso ndi makoswe amasonyeza ntchito yabwino ya anabolic ndiye testosterone propionate pa mlingo womwewo, ndi ntchito yochepa ya androgenic. Pa mlingo wapamwamba BMS-564929 ufa wofiira umalepheretsa hypothalamus ndi \ kapena pituary ndipo motere kumachepetsa kutseka kwa LH ndi FSH.

Pulogalamu ya XMS yovuta kwambiri ya BMS-564929 ndi LBD ya reception of androgen imasonyeza kusiyana pakati pa ufa wa BMS-564929 ndi dihydrotestosterone pochita mgwirizano ndi LBD ya receptor. Kusiyanasiyana uku kumawoneka kuti ndi kwakukulu mokwanira kuti athetse mgwirizano wa zotsatira za anabolic mu minofu osati mtheradi wa androgenic mu prostate. Sindinadziwe bwinobwino momwe mungalongosole kusiyana konse.

BMS-564929 powder ndiyomwe imapezeka pokhapokha ndi kusintha kwa kagayidwe kachakudya kamakhala pang'onopang'ono ndiye mu proionamide SARM's. Nthawi yochepa ya moyo imasiyanasiyana ndi 8 mpaka maola 14, ndipo chiwerengero chochepa chimatha.

Chenjezo pa BMS-564929 powder

BMS-564929 ufa ndifukufuku wofufuza ndi androgen receptor modulator (SARM) yomwe ikupangidwa ndi Bristol-Myers Squibb kuti athe kuchiza zizindikiro za kuchepa kwa zaka zowonjezera kwa zaka ndi amuna ("andropause"). Zizindikiro izi zingaphatikizepo kupsinjika maganizo, kutayika kwa minofu ndi mphamvu, kuchepetsa ku libido ndi matenda otupa mafupa. Chithandizo ndi testosterone yodabwitsa ndi yothandiza kuthana ndi zizindikirozi koma zimakhudzana ndi zotsatira zosiyana siyana, zomwe zimawopsa kwambiri ndi kukula kwa prostate gland, zomwe zingayambitse khansa ya prostatic hypertrophy komanso khansara ya prostate. Izi zikutanthauza kuti pali zofunikira zothandizira orogen receptor modulators, omwe amachititsa zotsatira za anabolic m'magulu ena monga minofu ndi mafupa, koma popanda kukhudzidwa ndi androgen receptors mu prostate.

Maumboni ena

BMS-564929 powder ndisankhidwa ndi atrogen receptor (AR) modulator ndi Ki chiwerengero cha 2.11 ± 0.16 nM.
A AR ndi mtundu wa nuclear nucleus yomwe imayambitsidwa ndi mahomoni a androgenic, testosterone, kapena dihydrotestosterone. Ntchito yofunikira ikutsogolera mafotokozedwe a geni.
BMS-564929 ufa wofiira ndi minofu ya agonist ya AR ndi bicyclic hydantoin. BMS-564929 powder ndi pafupi 400 -sankha kwa AR vs. PR komanso kuposa 1000 pokha kusankha AR vs. GR, MR ndi ERα ndi β. Mu C2C12 myoblast cell line, BMS-564929 ufa wonyezimira umasonyeza mphamvu ya 0.44 ± 0.03 nM poyerekeza ndi 2.81 ± 0.48 nM kuyeza kwa testosterone.
Mu makoswe amphongo, yaiwisi ya BMS-564929 imakhala yochuluka kwambiri kuposa testosterone (T) popititsa patsogolo kukula kwa mtengowo, ndipo imasankha minofu ndi Prostate. Chifukwa cha mphamvu zake zamakono ndi minofu yosankha, BMS-564929 powder imayembekezeredwa kuti ikhale ndi zotsatira zothandiza zachipatala mu minofu ndi minofu ina ndi njira yabwino kwambiri yotetezera.

Nkhumba ya BMS-564929 yaiwisi

10grams yayamba.
Funso labwino kwambiri (mkati mwa 1kg) lingatumizedwe mu maola a 12 mutatha kulipira.
Kuti mukhale wamkulu (mkati mwa 1kg) mukhoza kutumizidwa mu tsiku la ntchito 3 mutatha kulipira.

Malonda Odziwika a BMS-564929

Kuti aperekedwe m'tsogolomu.


Mungagule bwanji ufa wa BMS-564929 kuchokera ku AASraw

1.Kutiwuza ife ndi imelo yathu kafukufuku, kapena skype pa intanetiwoimira makasitomala (CSR).
2.Zotipatseni ife afunsidwa zambiri ndi adiresi yanu.
3.Our CSR idzakupatsani inu ndondomeko, nthawi yobwezera, nambala yotsatira, njira yobweretsera ndi tsiku lofika kufika (ETA).
4.Payment yachitidwa ndipo katunduyo adzatumizidwa mu maola a 12 (Kukonzekera mkati mwa 10kg).
5.Goods inalandira ndi kupereka ndemanga.


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COA

COA 627530-84-1 BMS-564929 ufa AASRAW

HNMR

Tili ndi BMS-564929 powder supplie, BMS-564929 ufa wogulitsa, BMS-564929-powder (627530-84-1) hplc =98% | Ikani ma Reagents a R & D

Maphikidwe

Maphikidwe a mpweya wa BMS-564929:

Kuti mufunse Wotumikira Wathu Woimira Wathu (CSR) kuti mudziwe zambiri, kuti muwone.

Mafotokozedwe ndi zolemba zamagulu

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