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Entecavir hydrate ufa

mlingo:
5.00 kuchokera 5 kutengera 1 kasitomala mlingo
SKU: 209216-23-9. Category:

AASraw ili ndi kaphatikizidwe ndi kupanga kupanga kuchokera ku gramu kupita ku masentimita akuluakulu a Entecavir hydrate powder (209216-23-9), pansi pa malamulo a CGMP ndi dongosolo loyendetsa khalidwe labwino.

Mafotokozedwe Akatundu

Entecavir hydrate video


Yaikulu Entecavir hydrate ufa Anthu oyambirira

Name: Entecavir hydrate ufa
CAS: 209216-23-9
Makhalidwe a Maselo: C12H17N5O4
Kulemera kwa maselo: 295.29
Melt Point: 220-225 ° C
Kusungirako nyengo: -20 ° C Freezer
mtundu; Oyera kuti achoke woyera wa ufa wa Crystalline


Mpweya wa Entecavir wakuda wambiri mumagwiritsidwe ntchito

Mayina

Baraclude

Ntchito yotchedwa Entecavir hydrate

Mavitamini a Entecavir ndi a deoxyguanosine a nucleoside analog ndi mankhwala oletsa tizilombo toyambitsa matenda (EC50 = 3.7 nM motsutsana ndi kachilombo ka hepatitis B (HBV) m'ziwalo zogwidwa ndi chiwindi cha 2.2.15). In vitro, mawonekedwe opangira mavitamini a Entecavir hydrate yaiwisi ya ufa, Entecavir hydrate powder triphosphate, amasonyeza kuti apamwamba kwambiri a HBV DNA polymerase kuposa chilengedwe cha guanosine triphosphate pansi ndipo amalepheretsa kubwereza kwa HBV DNA pazigawo za 3 pa njira yobwereza: kusindikizira, ndi DNA yodalira DNA. Mankhwala opangira mankhwala a Entecavir otulutsa ufa wofiira amatha kuwonetseredwa ndi mtundu wa HBV. Ntchito inagwiridwa pa maphunziro a I / II omwe amapezeka pachiyambi komanso ufa wa Entecavir hydrate analandira chilolezo kuchokera ku US Food and Drug Administration pofuna kuchiza anthu achikulire omwe ali ndi matenda a chiwindi.

Entecavir imatulutsa ufa wosalala (ETV), wogulitsidwa pansi pa dzina lakuti Baraclude, ndi mankhwala oletsa tizilombo toyambitsa matenda omwe amagwiritsidwa ntchito pochiza matenda a hepatitis B (HBV). Kwa iwo omwe ali ndi HIV / AIDS ndi HBV mankhwala ochepetsa ma ARV amayenera kugwiritsidwanso ntchito. Mavitamini a Entecavir amatengedwa pakamwa ngati piritsi kapena yankho.

Zotsatira zoyipa zimaphatikizapo kupweteka mutu, kunyozetsa, shuga yambiri ya magazi, ndi ntchito ya impso yotsika. Zotsatira zoopsa zikuphatikizapo kukulitsa kwa chiwindi, kuchuluka kwa magazi a lactate, ndi kutupa kwa chiwindi ngati mankhwala atayimitsidwa. Ngakhale kuti zikuwoneka kuti palibe vuto lililonse pogwiritsa ntchito panthawi yoyembekezera, kugwiritsa ntchito izi sikunaphunzire bwino. Entecavir hydrate ufa wochuluka uli mu nucleoside reverse transcriptase inhibitors (NRTIs). Zimateteza kachilombo ka hepatitis B kuti iwonjezeke ndi kulepheretsa reverse transcriptase.

Mavitamini a Entecavir amagwiritsidwa ntchito kwambiri pochiza matenda akuluakulu a chiwindi a anthu akuluakulu ndi ana omwe ali ndi zaka 2 ndi zaka zowonjezereka ndi kubwereza kachilombo koyambitsa matendawa komanso umboni wa matenda opatsirana omwe ali ndi mavitamini a chiwindi. Amagwiritsidwanso ntchito popeweratu HBV kukonzanso pambuyo pa kuika chiwindi ndi kuchiza odwala kachilombo ka HIV. Entecavir hydrate yaiwisi imakhala yogwira ntchito yolimbana ndi kachilombo koyambitsa matenda a HIV, koma sichivomerezeka kuti agwiritsidwe ntchito pa odwala HIV-HBV omwe alibe kachilombo ka HIV [9] momwe angasankhire kuti asamalimbane ndi lamivudine ndi emtricitabine mu HIV.

Mphamvu ya ufa wa Entecavir hydrate yakhala ikuphunziridwa mu mayesero angapo, aŵiri-akhungu, a multicentre. Entecavir hydrate phala pakamwa ndi othandiza ndipo ambiri amalekerera mankhwala.

Entecavir hydrate ufa wochuluka amatengedwa pakamwa ngati piritsi kapena yankho. Mlingo umachokera kulemera kwa munthu. Yankho likulimbikitsidwa kwa ana kuposa zaka 2 omwe amayeza mpaka 30 makilogalamu. Mankhwala a Entecavir hydrate amalimbikitsidwa pa chopanda kanthu m'mimba osachepera maola 2 asanayambe kudya kapena atadya, nthawi zambiri nthawi imodzi. Siligwiritsidwe ntchito kwa ana osakwana zaka 2. Kusintha kwazitsamba kumalimbikitsidwanso kwa anthu omwe ali ndi ntchito ya impso yotsika.

Chenjezo pa Entecavir hydrate powder

Ambiri omwe amagwiritsa ntchito ufa wa Entecavir hydrate amakhala ndi zotsatira zochepa. Zotsatira zoyipa zambiri zimaphatikizapo kumutu, kutopa, chizungulire, ndi mseru. Zovuta zochepa zomwe zimachitika zimaphatikizapo vuto logona ndi m'mimba zizindikiro monga mimba yowawa, kutsegula m'mimba, ndi kusanza.

Zotsatira zoyipa kuchokera ku Entecavir hydrate ufa wochuluka ndi lactic acidosis, mavuto a chiwindi, kukulitsa kwa chiwindi, ndi mafuta m'chiwindi.

Mayeso a Laboratory angasonyeze kuwonjezeka kwa alanine transaminase (ALT), hematuria, glycosuria, ndi kuchuluka kwa lipase. Kuwunika nthawi ndi nthawi za hepatic function ndi hematology akulimbikitsidwa.

Maumboni ena

Mavitamini a Entecavir ndi a analog a 2-deoxyguanosine omwe amachititsa kuti tizilombo toyambitsa matenda a hepatitis B (HBV). Entecavir hydrate yai yaiwisi yowonjezera yowonjezeredwa mu vivo ku 5-triphosphate metabolite. Pachifukwachi, mawonekedwe a triphosphate amapikisana ndi gawo lachilengedwe la deoxyguanosine triphosphate (dGTP) la kuikidwa m'thupi la DNA. Kuphatikizidwa kwa mankhwala a triphosphate opangidwa ndi entabilite a Entecavir hydrate amawononga reverse transcriptase (RT) yodalirika ya RNA yodalirika ya HBV DNA polymerase, motero, kubwezeretsedwa kwa tizilombo toyambitsa matenda a DNA ndi kulemba.

Entecavir hydrate ufa wofiira ndi guanosine nucleoside analogue yomwe imagwiritsidwa ntchito pochiza matenda odwala matenda a chiwindi (HBV). Mankhwala otchedwa Entecavir hydrate operesi angaphatikizepo ndi flares ya chiwindi cha hepatitis B pamapeto kapena pambuyo pa mankhwala, koma sanagwirizane ndi zoopsa za chiwindi.

Entecavir imatulutsa ufa wochuluka

10grams yayamba.
Funso labwino kwambiri (mkati mwa 1kg) lingatumizedwe mu maola a 12 mutatha kulipira.
Kuti mukhale wamkulu (mkati mwa 1kg) mukhoza kutumizidwa mu tsiku la ntchito 3 mutatha kulipira.

Malonda a Entecavir hydrate

Kuti aperekedwe m'tsogolomu.


Momwe mungagulire ufa wa Entecavir hydrate kuchokera ku AASraw

1.Kutiwuza ife ndi imelo yathu kafukufuku, kapena skype pa intanetiwoimira makasitomala (CSR).
2.Zotipatseni ife afunsidwa zambiri ndi adiresi yanu.
3.Our CSR idzakupatsani inu ndondomeko, nthawi yobwezera, nambala yotsatira, njira yobweretsera ndi tsiku lofika kufika (ETA).
4.Payment yachitidwa ndipo katunduyo adzatumizidwa mu maola a 12 (Kukonzekera mkati mwa 10kg).
5.Goods inalandira ndi kupereka ndemanga.


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COA

HNMR

Mavitamini a Entecavir (209216-23-9) ≥98% | Ikani ma Reagents a R & D

Maphikidwe

Entecavir hydrate ufa wophika Maphikidwe:

Kuti mufunse Wotumikira Wathu Woimira Wathu (CSR) kuti mudziwe zambiri, kuti muwone.

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