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Fungo la febuxostat (144060-53-7)

mlingo:
5.00 kuchokera 5 kutengera 1 kasitomala mlingo
SKU: 144060-53-7. Category:

AASraw ili ndi kaphatikizidwe ndi kapangidwe kake kuchokera ku gramu mpaka kulemera kwa febuxostat powder (144060-53-7), pansi pa malamulo a CGMP ndi dongosolo loyendetsa khalidwe labwino.

Febuxostat ufa amagwiritsidwa ntchito pochizira gout. Gout ndi mtundu wa nyamakazi imene uric acid, chinthu chobadwa mwachibadwa m'thupi, chimamangiriza m'magulu ndipo chimayambitsa modzidzimutsa wofiira, kutupa, ululu, ndi kutentha mumodzi kapena zingapo. Mafuta a febuxostat ndi gulu la mankhwala omwe amatchedwa xanthine oxidase inhibitors.

Mafotokozedwe Akatundu

Pulogalamu ya fungo ya Febuxostat


Yaikulu Febuxostat ufa Anthu oyambirira

Name: Febuxostat ufa
CAS: 144060-53-7
Makhalidwe a Maselo: C16H16N2O3S
Kulemera kwa maselo: 316.37
Melt Point: 238-239 ° C
Kusungirako nyengo: Firiji
mtundu; Yoyera kapena kuchotsa nyemba yakuyera ya Crystalline


Mphungu yamphongo ya Febuxostat m'kugwiritsidwa ntchito

Mayina

Mayina Ajambula: Uloric
Dzina lachibadwa: Febuxostat powder (Kutchulidwa: fe BUX oh stat)

Katundu wa febuxostat powder

Mafuta a febuxostat ndi mankhwala omwe amagwiritsidwa ntchito popewera gout. Gout ndi mtundu wa nyamakazi imene uric acid imamangirira mmalo mwake ndipo imayambitsa kuzunzidwa mwadzidzidzi kwa redness, kutupa, kupweteka, ndi kutentha mumodzi kapena zingapo. Fubuxostat ufa ndi gulu la mankhwala lotchedwa xanthine oxidase inhibitors. Zimagwira ntchito pochepetsa kuchuluka kwa uric acid omwe amapangidwa m'thupi.

Fungo la febuxostat limafika papepala. Zimatengedwa kamodzi tsiku ndi tsiku, kapena popanda chakudya.

Zotsatira zoyipa zimaphatikizapo kunyoza ndi kupweteka.

Fungo la febuxostat lingayambitse chizungulire ndi kusokoneza masomphenya. Osayendetsa galimoto kapena kugwiritsa ntchito makina olimba mpaka mutadziwa mmene febuxostat ufa umakukhudzirani.

Kodi mlingo wa febuxostat ufa ndi chiani?

Kugwiritsa Ntchito Mayi Achikulire Kuti Muwope
Mlingo woyamba: 40 mg mlomo kamodzi patsiku
-Koma serum acid level ndi yaikulu kuposa 6 mg / dL patatha masabata a 2, yonjezerani mlingo kwa 80 mg pamlomo pamodzi kamodzi
Mlingo wokonzekera: 40 kwa 80 mg mlomo kamodzi patsiku

Comments:
-Kodi mankhwalawa ayenera kuchitika pambuyo poti gout flare yayamba kwambiri.
-Zowopsa zimatha chifukwa cha kuwonjezeka kwamtundu wa makoswe, makamaka pa nthawi yoyamba; Gout flare prophylaxis ndi anti-steroidal anti-inflammatory kapena colchicine ikulimbikitsidwa ndipo ikhoza kukhala yopindulitsa kwa miyezi 6.
-Ndipo ma asidi a asidi angayang'anitse mwamsanga masabata a 2 atayamba mankhwalawa.

Gwiritsani ntchito: Kusamalidwa kosatha kwa matenda opatsirana pogonana kwa odwala omwe ali ndi gout

Zosintha Zosamba za Renal
Kusalumikiza Kwambiri kwa Renal (CrCl 30 kwa 89 mL / min) Palibe kusintha komwe kunalangizidwa.
Kulephera Kwambiri Kwambiri Kwambiri (CrCl 15 kwa 29 mL / min): Mlingo wa tsiku ndi tsiku ndi 40 mg / tsiku.

Dzira la Chiwindi Kusintha
Chiwopsezo Chamakono Chosokoneza Chiwindi (Kalasi ya A Child-Bugh A ndi B): Palibe kusintha komwe kunatchulidwa.
Kuwopsa kwa Chiwindi (Child-Pugh Class C): Gwiritsani ntchito mosamala.

-Kodi odwala omwe amayamba maulendo a ALT amaposa 3 nthawi zopitirira (3 x ULN): Osokoneza mankhwala; musayambirane popanda kufotokoza kwina kwa zovuta za ALT.
-Kodi odwala omwe amayamba kukhala ndi magulu a ALT akuluakulu kuposa 3 x ULN ndi bilirubin wamkulu kuposa 2 x ULN: Mankhwalawa ayenera kuthetsedwa ndipo asayambirenso mwa odwala popanda njira zina zofunikira.
-Kodi odwala omwe ali ndi ALT ang'onoang'ono kapena apamwamba a bilirubin ndipo ali ndi chifukwa china choyenera: Gwiritsani ntchito mosamala.

Kusintha kwa Mitsempha
Gout:
-Zomwe zimapangidwe ndi kuchepetsa ndi kusunga maselo a serum uric pansi pa 6 mg / dL.
-Ngati wodwalayo sakulandira samuyamu ya asidi osachepera 6 mg / dL pambuyo pa 2 kwa masabata a 4, kuwonjezeka kwa mlingo n'koyenera.
- Mliri waukulu: 80 mg / tsiku

Kugwiritsidwa ntchito kosagwirizana ndi mercaptopurine / azathioprine kumatsutsana.

Momwe febuxostat ufa amagwirira ntchito

Mafuta a febuxostat amapezeka m'gulu la mankhwala otchedwa xanthine oxidase inhibitors. Gulu la mankhwala ndi gulu la mankhwala omwe amagwira ntchito mofananamo. Mankhwalawa amagwiritsidwa ntchito pochita zinthu zofanana.
Mafuta a febuxostat amachepetsa uric asidi podutsa xanthine oxidase. Xanthine oxidase ndi puloteni yomwe imathandiza thupi lanu kupanga uric acid kuchokera ku xanthine. Maseŵera apamwamba a uric acid m'magazi anu angayambitse gout.

chenjezo

Musagwiritse ntchito mankhwalawa ngati muli ndi mankhwala enaake, ngati muli ndi mankhwala a azathioprine (Azasan, Imuran), mercaptopurine (Purinethol), ortheophylline (Elixophyllin, TheoCap, Theochron, Uniphyl).

Musanayambe kudya fungo la febuxostat, uzani dokotala ngati muli ndi matenda a impso, matenda a chiwindi, matenda a mtima, khansara, matenda a mtima wa Lesch-Nyhan, mbiri ya matenda a mtima kapena stroke, kapena ngati munalandirapo chiwalo.

Mutha kukhala ndi kuwonjezeka kwa zizindikiro za matenda a gout pamene mutangoyamba kumwa mphutsi ya febuxostat. Kuti mupeze zotsatira zabwino, pitirizani kumwa mankhwala monga momwe mwalangizira. Dokotala wanu angapereke mankhwala ena a gout omwe mungagwiritse ntchito m'miyezi yoyamba ya 6 ya mankhwala ndi febuxostat powder.

Kuti mutsimikize kuti mankhwalawa akuthandizani matenda anu, magazi anu angafunike kuyesedwa kawirikawiri. Pitani kuchipatala nthawi zonse.

Fungo la Febuxostat Raw

10grams yayamba.
Funso labwino kwambiri (mkati mwa 1kg) lingatumizedwe mu maola a 12 mutatha kulipira.
Kuti muyambe kukonzekera mukhoza kutumizidwa mu masiku a ntchito 3 mutatha kulipira.

Malonda a ufa wa febuxostat

Kuti aperekedwe m'tsogolomu.

Kodi febuxostat ufa uli ndi zotsatira zoyipa

Pezani chithandizo chamankhwala chodzidzidzika ngati muli ndi zizindikiro izi zotsutsa: ming†™ oma; kupuma kovuta; Kutupa kwa nkhope, milomo, lilime, kapena mmero.

Aitaneni dokotala mwamsanga ngati muli ndi zotsatira zoopsa monga:

kupweteka pachifuwa kapena kumverera kwakukulu, kupweteka kufalikira kumanja kapena paphewa, kunyoza, kutuluka thukuta, kumverera kwakukulu;
kusowa mwadzidzidzi kapena kufooka, makamaka mbali imodzi ya thupi;
kupweteka kwa mutu, kusokonezeka, mavuto ndi masomphenya, kulankhula, kapena kusamala; kapena
kupweteka kwa m'mimba, kutentha thupi, kusowa kwa njala, mitsempha yamdima, zojambula zadongo, jaundice (khungu la khungu kapena maso).
Zotsatira zochepa zoopsa zingaphatikizepo izi:

chisokonezo;
kupweteka pamodzi, kutupa, kapena kuuma;
kupweteka kwa khungu; kapena
chizungulire.


Kodi kugula febuxostat ufa kuchokera ku AASRAW

1.Kutiwuza ife ndi imelo yathu kafukufuku, kapena skype pa intanetiwoimira makasitomala (CSR).
2.Zotipatseni ife afunsidwa zambiri ndi adiresi yanu.
3.Our CSR idzakupatsani inu ndondomeko, nthawi yobwezera, nambala yotsatira, njira yobweretsera ndi tsiku lofika kufika (ETA).
4.Payment yachitidwa ndipo katunduyo adzatumizidwa mu maola a 12 (Kukonzekera mkati mwa 10kg).
5.Goods inalandira ndi kupereka ndemanga.


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COA

HNMR

Ndife febuxostat ufa supplie, Febuxostat powder powulitsa, Raw Febuxostat ufa (144060-53-7) hplc =98% | Gwiritsani ntchito ma Reagents a R & D HNMR

Maphikidwe

Mapuloteni a FUWS

Kuti mufunse Wotumikira Wathu Woimira Wathu (CSR) kuti mudziwe zambiri, kuti muwone.

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