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Nuciferine ufa

mlingo:
5.00 kuchokera 5 kutengera 1 kasitomala mlingo
SKU: 475-83-2. Category:

AASraw ili ndi kaphatikizidwe ndi kupanga kupanga kuchokera ku gramu kuti ikhale yaikulu ya Nuciferine powder (475-83-2), pansi pa lamulo la CGMP ndi dongosolo loyendetsa khalidwe labwino.

Nuciferine ufa ndi alkaloid yomwe imapezeka mu zomera Nymphaea caerulea ndi Nelumbo nucifera. Ili ndi mbiri yogwirizana ndi dopamine receptor blockade.Imapangitsa sedation, hypothermia, ptosis, ndi (muyezo waukulu) catalepsy; imalepheretsa kuchita masewera olimbitsa thupi, kupewera koyenera, amphetamine poizoni komanso osakanikirana. Nuciferine ufa ikhoza kuthetsanso morphine analgesia. Mlingo wowonongeka pakati pa mbewa ndi 289 mg / kg. Ndimagwirizana ndi apomorphine.

Mafotokozedwe Akatundu

Nuciferine powder video


Mpaka wa Nuciferine powder

Name: Nuciferine ufa
CAS: 475-83-2
Makhalidwe a Maselo: C19H21NO2
Kulemera kwa maselo: 295.38
Melt Point:
Kusungirako nyengo: Firiji
mtundu; Yoyera kapena kuchotsa nyemba yakuyera ya Crystalline


Mphungu yaikuru ya Nuciferine powder

Mayina

(6aR)-1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline, Nuciferine powder (CAS 475-83-2)

Ntchito Yowonjezera ya Nuciferine

Nuciferine ufa ndi alkaloid yomwe imapezeka mkati mwa zomera Nymphaea caerulea ndi Nelumbo nucifera. Ili ndi mbiri yogwirizana ndi dopamine receptor blockade.Imapangitsa sedation, hypothermia, ptosis, ndi (muyezo waukulu) catalepsy; imalepheretsa kuchita masewera olimbitsa thupi, kupewera koyenera, amphetamine poizoni komanso osakanikirana. Nuciferine ufa ikhoza kuthetsanso morphine analgesia. Mlingo wowonongeka pakati pa mbewa ndi 289 mg / kg. Ndimagwirizana ndi apomorphine.

1.Nuciferine yaiwisi yaiwisi ndi yaikulu kwambiri ya aporphine alkaloid kuchokera masamba a N. nucifera Gaertn omwe ali ndi anti-hyperlipidemia, anti-hypotensive, anti-arrhythmic, ndi insulin secretagogue ntchito.
2. Nuciferine powder ndi wofunikira kwambiri wothandizira mankhwala ochizira matenda okhudzana ndi kunenepa kwambiri, kupyolera mukulitsa matenda a HFD-omwe amachititsa kuti matenda a dyslipidemia komanso chiwindi cha chiwindi ndi kuvulala.
3. Nuciferine ufa wofiira ukhoza kukhala wotheka kupewa ndi kuchiza matenda a hyperuricemia ndi kutupa kwa impso.
4. Nuciferine powder ali ndi mphamvu yaikulu pamagwiridwe onse a endothelium ndi-osalongosoka, amasonyeza kuti Nuciferine ufa akhoza kukhala ndi zotsatira zochiritsira matenda opatsirana okhudzana ndi matenda osokoneza bongo.
5. Nuciferine ufa wofiira, wochokera ku Nelumbo nucifera, ukhoza kuyambitsa magawo awiri a insulini kusungunuka m'madera omwe ali kutali mwa kutseka njira za potassium-adenosine triphosphate, kufotokoza zotsutsana ndi matenda a shuga a Nelumbo nucifera.
6. Nuciferine powder (CAS 475-83-2) imaletsa zotsatira zowonongeka kwa chikonga zogwiritsa ntchito Wnt / β-catenin mu kansa yaing'ono ya mapapu ya m'mapapo, imapereka njira yatsopano yopewera ndi mankhwala a NSCLC.

Chenjezo pa Mafuta a Nuciferine

Kupereka yosungirako kunanenedwa pa mankhwala opangidwa ndi vinyo ndipo chiwindichi chimasindikizidwa mwamphamvu, mankhwalawa akhoza kusungidwa kwa miyezi 24 (2-8C).
Kumene kuli kotheka, muyenera kukonzekera ndikugwiritsa ntchito njira zothetsera vutoli tsiku lomwelo. Komabe, ngati mukufuna kupanga njira zowonjezerapo, tikukulimbikitsani kuti muzisunga yankho ngati zida zowindikizidwa mwamphamvu pa -20C. Kawirikawiri, izi zidzagwiritsidwa ntchito kwa milungu iwiri. Musanagwiritse ntchito, ndipo musanatsegule viala timalangiza kuti mulole kuti mankhwala anu agwirizane ndi kutentha kwa osachepera ola la 1.

Katundu wa mankhwalawa akhoza kukhala atasokonezeka panthawi ya kayendetsedwe ka kayendedwe ka mankhwala, zomwe zimapangitsa mankhwala omwe amamatira pamutu kapena kapu ya vial. Chotsani chikhocho kuchokera mumapangidwe ake ndipo pang'anani pang'onopang'ono kuti mulole mankhwalawo agwe pansi pa vial. Pogwiritsa ntchito mankhwala osokoneza bongo, XIUMX-200 RPM imatha kusonkhanitsa madzi pansi pa vial. Yesetsani kupewa kutayika kapena kusokonezeka pamene mukuchita.

Maumboni ena

In Vitro ndi In Vivo Maonekedwe a Alkaloid Nuciferine ufa

(1) mwachidule
Lotus yopatulika (Nelumbo nucifera) ili ndi mankhwala ambiri a phytochemicals ndipo ili ndi mbiri ya ntchito ya anthu. Kuti mudziwe kuti ndi zinthu ziti zomwe zimayambitsa zotsatira za psychotropic, tinagwiritsa ntchito maulosi a silico a phytochemicals. Nuciferine ufa wofiira, chigawo cha alkaloid cha Nelumbo nucifera ndi Nymphaea caerulea, chinali ndi mawonekedwe ofanana kwambiri ndi mankhwala opatsirana. Kuphunzira kwathu kumapanga Nuciferine ufa pogwiritsa ntchito vitro ndi mu vivo mankhwala apamwamba.

(2) Njira
Nuciferine yaiwisi yaiwisi yoyamba inali ndi silico pogwiritsira ntchito kufanana pamodzi, ndipo kenaka inatsatiridwa ndi kuwonetseratu ndikugwiritsidwa ntchito pogwiritsa ntchito Psychoactive Drug Screening Program ya National Institute of Mental Health. Nuciferine ufa ndiye anayesedwa mu vivo pamutu wokhotakhota mutu, chiwonetsero choyambirira, chiwonetsero cha mankhwala osokoneza bongo, komanso mankhwala osokoneza bongo.

(3) Zotsatira
Nuciferine powder amagwira ntchito yofanana ndi mankhwala omwe alipoprazole ngati antipsychotic. Nuciferine ufa wofiira anali wotsutsa pa 5-HT2C, 5-HT2C, ndi 5-HT2B, agonist osagwirizana pa 5-HT7, agonist ochepa pa D2, D5 ndi 5-HT6, agonist pa 5-HT1A ndi D4 amalandira, ndipo analetsa dopamine transporter. Mu mitundu yambiri ya mankhwala omwe amagwiritsa ntchito mankhwala osokoneza bongo, Nuciferine ufa wathyolapo zowonongeka ndi zotsatira zotsutsa za 5-HT2A agonist, m'malo mwachisokonezo cha clozapine, kupititsa patsogolo amphetamine kumapangitsa ntchito zogwirira ntchito, kulepheretsa phencyclidine (PCP) anapulumutsidwa chifukwa cha kusokonezeka kwa PCP koyambitsa matenda osapangidwira popanda kupangidwira kwa catalepsy.

(4) Zotsatira
Nkhope ya Nuciferine yaiwisi yofiira inali yofananitsa koma si yofanana ndi yomwe inagwiritsidwa ntchito ndi mankhwala ovomerezeka omwe amavomereza kuti mankhwala a Nuciferine ali ndi zochita zotsutsana ndi antipsychotic.

Nkhiferine Raw Powder (CAS 475-83-2)

10grams yayamba.
Funso labwino kwambiri (mkati mwa 1kg) lingatumizedwe mu maola a 12 mutatha kulipira.
Kuti mukhale wamkulu (mkati mwa 1kg) mukhoza kutumizidwa mu tsiku la ntchito 3 mutatha kulipira.

Malonda a Nuciferine Wofiira Wakuda

Kuti aperekedwe m'tsogolomu.


Mungagule bwanji Nuciferine powder (CAS 475-83-2) kuchokera kwa AASraw ogulitsa

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COA

COA 475-83-2 Nuciferine ufa AASRAW

HNMR

Mphungu ya Nuciferine (475-83-2) hplc≥98% | AASraw ogulitsa

Maphikidwe

Maphikidwe a Nukiferine Raw Powder:

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