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Pregabalin ufa

mlingo: SKU: 148553-50-8. Category:

AASraw ndi katswiri wopanga Pregabalin ufa womwe uli ndi labu yodziyimira pawokha komanso fakitale yayikulu monga chithandizo, zonse zopanga zizichitika motsogozedwa ndi CGMP ndikuwongolera kachitidwe kabwino. Dongosolo loperekera ndi lokhazikika, maoda ogulitsa ndi ogulitsa ndi ovomerezeka.

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Video ya Pregabalin powder

 

 


 

Makhalidwe Oyambira

Name mankhwala: Pregabalin ufa
Nambala ya CAS: 148553-50-8
Makhalidwe a Maselo: C8H17NO2
Kulemera kwa maselo: 159.23
Melt Point: 194-196 ° C
mtundu; White kapena woyera ufa wa kristalo
Kusungirako nyengo: RT

Ndemanga za Pregabalin Powder

Pregabalin ufa ndi ufa woyera umene umagwiritsidwa ntchito ngati mankhwala oletsa khunyu, wotchedwanso anticonvulsant. Zimagwira ntchito pochepetsa kugunda kwa ubongo komwe kumayambitsa kukomoka. Pregabalin ufa imakhudzanso mankhwala mu ubongo omwe amatumiza zizindikiro zowawa kudutsa dongosolo lamanjenje.

Pregabalin ufa amagwiritsidwa ntchito pochiza kupweteka kwa fibromyalgia, kapena kupweteka kwa mitsempha kwa anthu odwala matenda a shuga (diabetesic neuropathy), herpes zoster (post-herpetic neuralgia), kapena kuvulala kwa msana.

Pregabalin ufa amagwiritsidwanso ntchito ndi mankhwala ena kuti athetse kugwidwa pang'ono kwa anthu akuluakulu ndi ana omwe ali ndi mwezi wa 1. Pregabalin yaiwisi ya ufa ingagwiritsidwenso ntchito pazinthu zomwe sizinalembedwe mu bukhuli la mankhwalawa.

 

Pregabalin Mechanism of Action

Pregabalin ndi mankhwala a anticonvulsant omwe amagwiritsidwa ntchito pochiza ululu wa neuropathic ndi fibromyalgia, komanso pochiza kukomoka pang'ono kuphatikiza ndi anticonvulsants ena.

Ngakhale kuti kachitidwe kake sikunadziwike bwino, kafukufuku wokhudza mankhwala okhudzana ndi mapangidwe amasonyeza kuti kumangidwa kwa presynaptic kwa pregabalin ku magetsi a calcium ndi kofunika kwambiri pa antiseizure ndi antinociceptive zotsatira zomwe zimawonedwa mu zinyama.

Pomanga presynaptically ku alpha2-delta subunit ya voltage-gated calcium channels mu chapakati mantha dongosolo, pregabalin modulates kumasulidwa angapo excitatory neurotransmitters kuphatikizapo glutamate, substance-P, norepinephrine, ndi calcitonin jini peptide peptide.Kuonjezera apo, pregabalin imalepheretsa alpha2-delta subunit kuchokera ku malonda kuchokera ku dorsal root ganglia kupita ku nyanga ya msana, zomwe zingathandizenso kuti azichitapo kanthu. Ngakhale pregabalin ndi yochokera ku inhibitory neurotransmitter gamma-aminobutyric acid (GABA), samamanga mwachindunji ku GABA kapena benzodiazepine receptors.

 

Kugwiritsa / Ntchito a Pregabalin

❶ Pharmacological efficacy: Pregabalin ndi novelγ-aminobutyric acid (GABA) receptor agonist, akhoza kutsekereza njira za calcium zomwe zimadalira magetsi kuti achepetse kutulutsidwa kwa neurotransmitter.

❷ Chipatala chachikulu chochizira kupweteka kwapang'onopang'ono kwa neuropathic komanso gawo la chithandizo chamankhwala chapakatikati.

❸ Chithandizo cha khunyu popanga mankhwala odalirika kwambiri m'mankhwala ochizira bwino komanso osavuta. Angagwiritsidwenso ntchito pochiza ululu ndi nkhawa.

 

Zotsatira za Pregabalin

Monga mankhwala ambiri, Lyrica angayambitse zotsatira zochepa kapena zoopsa. Uwu si mndandanda wathunthu wa zotsatira zoyipa ndipo zina zitha kuchitika. Wothandizira zaumoyo akhoza kukulangizani za zotsatirapo. Ngati mukukumana ndi zotsatira zina, funsani wazachipatala kapena wothandizira zaumoyo.

 

Zotsatira Zogwirizana

Mutha kukumana ndi zotsatira zoyipa mukamamwa pregabalin. Zotsatira zoyipa za pregabalin ndizo:

▪ chizungulire

▪ kugona

▪ chisokonezo

▪ kusaona bwino

▪ kunjenjemera

▪ kusakhazikika poyenda

▪ kunenepa

▪ kudzimbidwa

▪ pakamwa pouma.

 

Zotsatira Zazikulu

Itanani wothandizira wanu nthawi yomweyo ngati muli ndi zotsatira zoyipa. Imbani 911 ngati zizindikiro zanu zikuwopseza moyo kapena ngati mukuganiza kuti muli ndi vuto lachipatala. Zotsatira zoyipa kwambiri komanso zizindikiro zake zingaphatikizepo izi:

▪ Kuganiza zodzipha kapena kufuna kudzipha: Zizindikiro zake zingaphatikizepo kufuna kudzipha, kuda nkhawa kwatsopano kapena kukulirakulirakulira, kulephera kugona, kukhumudwa, kuchita zinthu motsatira zilakolako zoopsa, ndiponso kusintha kwachilendo kwa maganizo kapena khalidwe.

▪ Kusamvana kwakukulu: Zizindikiro zake zingaphatikizepo kupuma movutikira, ming'oma, kutupa lilime, milomo, mkamwa, kapena mmero.

▪ Mavuto a mtima

▪ Mavuto aakulu a kupuma

Zotsatira zina zimatha kukhala bwino pakapita nthawi, pomwe zina monga chizungulire ndi kugona zimatha mpaka mutamwa mankhwalawa.

 

Pregabalin Storage

Anthu ayenera kusunga mankhwalawa pa kutentha kwa chipinda, pafupifupi madigiri 68 mpaka 77 madigiri Fahrenheit.

Ngati mukuyenda, nthawi zonse muzinyamula mankhwala anu ndipo sungani botolo lolembedwa ndi mankhwala kapena bokosi mu thumba lanu. Musasiye mankhwalawa m'galimoto yanu, makamaka kutentha kwambiri kapena kutentha kwambiri.

 

Malangizo Ogula Pregabalin Powder kuchokera ku AASraw sitepe ndi sitepe

♦ Pitani ku webusaiti ya AAS, sankhani ufa wa pregabalin womwe mukufuna, ndipo siyani mauthenga anu ndi mauthenga anu pa tsamba la AAS, kenaka perekani, AAS Customer Services idzakuyankhani mu maola a 12 mutalandira uthenga wanu, kenaka kambiranani mwatsatanetsatane.

♦ Ingotumizani imelo kapena tumizani mauthenga pa whatsapp kwa anthu omwe amagwira ntchito ku AAS ndikuwauza kuti mukufuna kugula ufa wa pregabalin kuchokera ku aasraw, kenako lankhulani mwatsatanetsatane, za chiyero, kuchuluka, Kutumiza, adilesi, sankhani malipiro oyenera, katundu akhoza kukhala. kutumizidwa mkati mwa maola 12 mutalipira, mutalipira, mudzalandira nambala yotsata, komanso ntchito yamakasitomala ya AAS idzakudziwitsani nthawi, ndiye kuti mumangofunika kukhala pansi momasuka, kudikirira phukusi lanu.

♦ AAS inali kampani ku China,Kuti mutetezeke, ngati muli ndi bwenzi ku China, muthanso kulola anzanu kuti aziyendera kampani yawo, lankhulani mwatsatanetsatane, ndikupeza zinthu zomwe mukufuna.

 

Reference

[1] Dworkin RH, O'Connor AB, Backonja M, et al. Pharmacologic management of neuropathic pain: malingaliro ozikidwa pa umboni. Ululu 2007;132:237-51.

[2] Finnerup NB, Jensen TS. Kugwiritsa ntchito kuchipatala kwa pregabalin pakuwongolera ululu wapakati pa neuropathic. Matenda a Neuropsychiatric ndi Chithandizo 2007; 3: 885-91.

[3] Kalso E, Aldington DJ, Moore RA. Mankhwala a neuropathic ululu. BMJ 2013;347:f7339.

[4] Mannix, Liam (December 18, 2018). “Mankhwala otchukawa amakhudzana ndi kumwerekera ndi kudzipha. N’chifukwa chiyani madokotala amapitirizabe kupereka mankhwala?” The Canberra Times. Zosungidwa kuchokera koyambirira pa Disembala 18, 2018. Zabwezedwa pa Disembala 18, 2018.

[5] Ngakhale, James W.; Willmore, James; Brumback, Roger A. (2009). Advanced Therapy mu Khunyu. PMPH-USA. p. 302. ISBN 978-1-60795-004-2.