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Pyridoxal-5-phosphate Monohydrate

mlingo:
5.00 kuchokera 5 kutengera 1 kasitomala mlingo
SKU: 41468-25-1. Category:

AASraw ili ndi kaphatikizidwe ndi kapangidwe kake kuchokera ku gramu kuti ikhale yopangidwa ndi Pyridoxal-5-phosphate Monohydrate (41468-25-1), pansi pa malamulo a CGMP ndi kayendedwe ka khalidwe labwino.

Pyridoxal-5-phosphate Monohydrate powder, Vitamini B6 metabolite yomwe imagwira ntchito monga coenzyme muzochita zowonongeka mwa kupanga chiyanjano chokhazikika pamodzi ndi magulu a lysine pa aminotransferase. Komanso amagwiritsidwa ntchito monga coenzyme muzochita zinazake zowonongeka ndi kuwonetsa. Angasinthe zitsulo zamapiritsi ndi mavitamini m'mapuloteni. Amatha kuletsa mapuloteni opangira mafuta ndi mavitamini a Ca2 +.

Mafotokozedwe Akatundu

Video ya Pyridoxal-5-phosphate Monohydrate


Pyridoxal-5-phosphate Monohydrate ofunika kwambiri

Name: Pyridoxal-5-phosphate Monohydrate
CAS: 41468-25-1
Makhalidwe a Maselo: C8H12NO7P
Kulemera kwa maselo: 265.16
Melt Point: 2-8 ° C
Kusungirako nyengo: Kutentha kwa Chipinda
mtundu; Pale Yellow Crystalline


Pyridoxal-5-phosphate Pulogalamu ya monohydrate

1. Mayina:
Maina a Mankhwala: Pyridoxal- 5'-phosphate monohydrate, 3-Hydroxy-2-methyl-5 - ([phosphonooxy] methyl) -4-pyridinecarboxaldehyde
Codecarboxylase
Maina Ena: Vitamini B6, Pyridoxal Phosphate, PLP

Pyridoxal-5-phosphate Monohydrate Ntchito

Vitamini B6 metabolite yomwe imagwira ntchito monga coenzyme mu kusintha kwa transamination mwa kupanga chiyanjano chokhazikika ndi magulu a lysine pa aminotransferase. Komanso amagwiritsidwa ntchito monga coenzyme muzochita zinazake zowonongeka ndi kuwonetsa. Angasinthe zitsulo zamapiritsi ndi mavitamini m'mapuloteni. Amatha kuletsa mapuloteni opangira mafuta ndi mavitamini a Ca2 +.

Kodi mlingo wa Pyridoxal-5-phosphate Monohydrate ndi chiani?

PLP ndiwothandiza popanga zitsulo zamagetsi ndi zitsulo zamagetsi komanso kugwira ntchito monga coenzyme mu zochitika za transamination mwa kupanga mgwirizano wazitsulo ndi magulu a lysine pa aminotransferase
PLP ndi mavitamini B6
Komanso amagwiritsidwa ntchito monga coenzyme muzochita zinazake zowonongeka ndi kuwonetsa

Momwe Pyridoxal-5-phosphate Monohydrate imagwira ntchito

Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), mavitamini B6, ndi coenzyme m'maganizo osiyanasiyana. Komiti ya Enzyme inalembetsa zochita zoposa 140 PLP-zofanana, zogwirizana ndi ~ 4% pazochitika zonse zosankhidwa. Kuchita bwino kwa PLP kumachokera ku mphamvu yake yokakamiza kumanga gawolo, ndiyeno kukhala ngati chothandizira cha electrophilic, motero kumatsimikizira mitundu yosiyana ya carbanionic reaction intermediates.

PLP imagwira ntchito monga coenzyme muzochitika zonse zowonongeka, ndipo mwazidzidzidzi, kutayidwa, ndi kusintha kwa machitidwe a amino acid. Gulu la aldehyde la PLP limapanga mgwirizano wothandizira (mkati mwa aldimine) ndi gulu la ε-amino la mtundu wina wa lysine wa aminotransferase enzyme. Gulu la α-amino la gawo la amino acid limapangitsanso gulu la ε-amino la malo otetezeka a malo a lysine mu njira yotchedwa transaldimination. Zomwe zimachokera kunja zimatha kutaya pulotoni, carbon dioxide, kapena amino acid kuti ikhale pakati pa quinoid, yomwe ingakhale ngati nucleophile mu njira zingapo zomwe zimayendera.

Mu transamination, pambuyo chisokonezo quinoid pakati amavomereza proton pa malo osiyana kuti akhale ketimine. Chotsitsacho chimachokera ku hydrolysed kuti gulu la amino likhalebe lovuta. Kuonjezera apo, PLP imagwiritsidwa ntchito ndi aminotransferase (kapena transaminases) zomwe zimachita shuga zachilendo monga perosamine ndi desosamine. Muzochita izi, PLP imayanjana ndi glutamate, yomwe imaika gulu la alpha-amino ku PLP kupanga pyridoxamine phosphate (PMP). PMP ndiye amachotsa nayitrojeni kwa shuga, kupanga ma shuga a amino.

PLP imakhudzidwanso ndi zochitika zosiyanasiyana monga beta dehydratase ndi GDP-4-keto-6-deoxymannose-3-dehydratase (ColD).

Amagwiranso ntchito mu condensation reaction mu heme kaphatikizidwe. Mapulogalamu amathandizira kutembenuka kwa levodopa mu dopamine, kumathandiza kutembenuka kwa glutamate yothandizira odwala matendawa ku GABA, ndipo amalola SAM kukhala decarboxylated kuti apange propylamine, yomwe imatsogolera polyamines.

chenjezo

Ichi ndi mawonekedwe a VITAMIN B 6 omwe amagwiritsidwa ntchito monga coenzyme poyambitsa amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Pa transamination ya amino acid, pyridoxal phosphate imatembenuzidwa kukhala pyridoxamine phosphate (PYRIDOXAMINE).
kuchokera ku MESH
Pyridoxal Phosphate ndi mavitamini B6 komanso coenzyme ya mavitamini ovomerezeka ambiri a pyridoxal phosphate (PLP). PLP ikuphatikizidwa mu kuchulukitsa mankhwala ochulukitsa mapuloteni, decarboxylation ndi machitidwe a deamination; Ndikofunika kuti kaphatikizidwe ka amino acid ndi amino acid metabolites, komanso chifukwa cha kaphatikizidwe ndi / kapena kupweteka kwa matenda ena, kuphatikizapo kutembenuka kwa glutamate ku gamma-aminobutyric asidi (GABA) ndi levodopa mu dopamine. PLP ikhoza kugwiritsidwa ntchito ngati chakudya chowonjezera pa vitamini B6. Magulu ochepetsetsa a PLP mu ubongo angayambitse matenda osokoneza ubongo.
Pharmacology kuchokera ku NCIt
Uwu ndiwo mavitamini B6 omwe amagwiritsidwa ntchito monga coenzyme poyambitsa amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Pa transamination ya amino acid, pyridoxal phosphate imatembenuzidwa kukhala pyridoxamine phosphate (pyridoxamine). - Pubchem; Pyridoxal-phosphate (PLP, pyridoxal-5'-phosphate) ndi cofactor ya ambiri enzymatic reaction. Ndiwo mavitamini B6 omwe ali ndi mankhwala atatu, pyridoxal, pyridoxamine ndi pyridoxine.

Pyridoxal-5-phosphate Mapulogalamu Ophwanya Mazira Omwe Amadziwika

Kuti mufunse Wotumikira Wathu Woimira Wathu (CSR) kuti mudziwe zambiri, kuti muwone.

Pyridoxal-5-phosphate Masoko Omwe Amagulitsa Maso

Kuti aperekedwe m'tsogolomu.

Kodi Pyridoxal-5-phosphate Monohydrate Ali ndi Zovuta Zonse

Pyridoxal Phosphate ndi mavitamini B6 komanso coenzyme ya mavitamini ovomerezeka ambiri a pyridoxal phosphate (PLP). PLP ikuphatikizidwa mu kuchulukitsa mankhwala ochulukitsa mapuloteni, decarboxylation ndi machitidwe a deamination; Ndikofunika kuti kaphatikizidwe ka amino acid ndi amino acid metabolites, komanso chifukwa cha kaphatikizidwe ndi / kapena kupweteka kwa matenda ena, kuphatikizapo kutembenuka kwa glutamate ku gamma-aminobutyric asidi (GABA) ndi levodopa mu dopamine. PLP ikhoza kugwiritsidwa ntchito ngati chakudya chowonjezera pa vitamini B6. Magulu ochepetsetsa a PLP mu ubongo angayambitse matenda osokoneza ubongo.


Zogula Pyridoxal-5-phosphate Monohydrate kuchokera ku AASraw

1.Kutiwuza ife ndi imelo yathu kafukufuku, kapena skype pa intanetiwoimira makasitomala (CSR).
2.Zotipatseni ife afunsidwa zambiri ndi adiresi yanu.
3.Our CSR idzakupatsani inu ndondomeko, nthawi yobwezera, nambala yotsatira, njira yobweretsera ndi tsiku lofika kufika (ETA).
4.Payment yachitidwa ndipo katunduyo adzatumizidwa mu maola a 12 (Kukonzekera mkati mwa 10kg).
5.Goods inalandira ndi kupereka ndemanga.


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COA

HNMR

Maphikidwe

Pyridoxal-5-phosphate Yowonjezera Madzi Maphikidwe

10grams yayamba.
Funso labwino kwambiri (mkati mwa 1kg) lingatumizedwe mu maola a 12 mutatha kulipira.
Kuti muyambe kukonzekera mukhoza kutumizidwa mu masiku a ntchito 3 mutatha kulipira.

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