Mphindi 30 Kudziwa Nootropic Pramiracetam-AASraw

Kodi Nootropic ndi Chiyani?

Mawuwa amatanthauza mankhwala achilengedwe kapena opanga omwe atha kukhala okhudza luso lamaganizidwe. Amatha kukhala azakudya zowonjezera, mankhwala opangidwa ndi mankhwala, kapena mankhwala akuchipatala. Zitsanzo za mankhwala a nootropic ndi Ritalin, cholimbikitsira chomwe chimagwiritsidwa ntchito pochizira ADHD kapena Memantine, mankhwala a matenda a dementia.

Zowonjezera zokuthandizani Kupititsa patsogolo nzeru, zaluso, komanso chidwi ndizopindulitsa kwambiri pampikisano wapano. Mutha kuwamva akutchedwa "mankhwala anzeru" koma ndizoposa pamenepo.

Mawu oti nootropic amachokera ku mizu yachi Greek: "nous", kutanthauza malingaliro, ndi "tropin", kutanthauza kutembenuka kapena kupindika (ngati mtsinje).

Zomwe zimawoneka mu Nootropics

Kuti mankhwala azikhala ngati nootropic, amafunika kukwaniritsa zofunikira. Mwambiri, nootropic yovomerezeka

• Imawonjezera kukumbukira
• Imasintha zomwe zimachitika mukapanikizika
• Kuteteza ubongo kuvulala kwakuthupi kapena kwamankhwala
• Imasintha ma cortical / subcortical control
• Ali ndi poyizoni wochepa kapena zoyipa zina

Zopanga zotsatirazi ndizomwe zidapangidwa posachedwapa, koma miyambo yakale yazachipatala ku China ndi India imawonetsa kugwiritsa ntchito mankhwala osokoneza bongo, ginkgo biloba, ndi zitsamba zina pazifukwa izi.

Chifukwa chiyani Pramiracetam Imadziwika?

Pramiracetam ndi gawo la banja la racetam, gulu lazinthu zopanga zomwe zimakhala ndi pyrrolidone phata. Mankhwala osokoneza bongo m'banja lino ndi anticonvulsants, memory, and enhancers.

Pramiracetam imakhudza kwambiri kupezeka kwa kukumbukira. Kafukufuku akuwonetsa kuti ndi njira yoteteza ku matenda. Mosiyana ndi mankhwala ambiri m'banja la racetam, mphamvu yake idayesedwa kwa achikulire athanzi. Makina ambiri a racetam adayesedwa kwa okalamba omwe akucheperachepera.

Ndi nootropic yamphamvu yokhala ndi zotsatira zokhalitsa zomwe zimamanga pakapita nthawi. Umboni wina ukuwonetsa kuti zitha kuthandizira kuvulala koopsa muubongo.

Pramiracetam Kufotokozera

Pramiracetam (N- [2- [di (propan-2-yl) amino] ethyl] -2- (2-oxopyrrolidin-1-yl) acetamide, CI-879, Pramistar, Neupramir, Remen) ndi nootropic yosungunuka mafuta. m'gulu la racetam.

Pramiracetam (CAS: 68497-62-1) yawonetsa kuti ndi yothandiza pochiza zovuta zamaganizidwe am'magazi amisala komanso zoyipa. Kuyesedwa kwa anthu omwe ali ndi vuto losakumbukira kwawonetsa kuti Pramiracetam imatha kukulitsa chikumbukiro. Ngakhale palibe maphunziro omwe akutsimikizira kuti ndi momwe zimakhalira ndi achinyamata athanzi, ambiri akuti akumva zovuta zakukumbukira komanso kukumbukira. Kufotokozera chifukwa chomwe Pramiracetam imathandizira kukumbukira, ndikuti yawonetsa kukulitsa kuyanjana kwa choline.

Mwasayansi, Choline molekyu woyambira wa neurotransmitter acetylcholine, yofanana kwambiri ndi vitamini ndipo ndi chopatsa thanzi. Choline amatha kupezeka muzomera zina kapena ziweto zina kapena mkaka. Kukhala ndi chakudya chopatsa thanzi motero kukhala ndi choline yokwanira pamodzi ndi ma racetams owonjezera monga Pramiracetam omwe amalimbikitsa kulanda kwa choline, atha kukhala ndi gawo labwino pamakumbukiro.

Pramiracetam ndimapangidwe amtundu wa racetam omwe amafanana ndi mamolekyulu a Piracetam. Idapangidwa koyamba mu 1984 chifukwa chakutha kwake kuteteza amnesia kuchokera ku magetsi. Poyerekeza ndi ena am'banja la racetam, Pramiracetam sifufuzidwa pang'ono koma ili ndi umboni woti imathandiza anthu.

M'maphunziro, Pramiracetam imawoneka ngati yothandiza itayesedwa nthawi yayitali isanachitike yomwe ingapangitse kuti ikhale yabwino kuwonjezerapo panthawi yamaphunziro kapena ntchito yayikulu pomwe kukumbukira kukumbukira ndi magwiridwe antchito zimathandiza. Maphunziro aumunthu amachirikiza lingaliro ili koma sakupereka umboni wokwanira mpaka lero.

Pramiracetam Njira yogwira ntchito

Monga ma racetams onse, njira zopangira pramiracetam sizimamveka bwino, makamaka chifukwa chosowa kafukufuku wambiri.

Komabe, kafukufuku wina wakale adafotokoza njira zingapo zotsatirazi:

▪ Angakulitse milingo ya acetylcholine (powonjezera choline wolowa m'maselo ndi 30-37%);

▪ Zitha kuwonjezera kuchuluka kwa nitric oxide muubongo;

▪ Zitha kuphatikizira mahomoni a adrenal monga aldosterone ndi cortisol (corticosterone);

Komabe, zambiri pazomwe tafotokozazi zimabwera makamaka kuchokera ku kafukufuku wazinyama - makamaka makoswe ndi mbewa - motero palibe malingaliro omveka omwe angapangidwe pakadali njira za pramiracetam muubongo wa ogwiritsa ntchito athanzi.

Pramiracetam ubwino

Pramiracetam ndi a nootropic woona, Zapangidwa makamaka kuti zithandizire kuzindikira. Ubwino wake ndi zotsatirapo zake ndi izi:

• Kusintha Kokomere

Pramiracetam ndi chitsimikiziro chokumbutsa chokulitsa, choyesedwa kwambiri pazaka makumi angapo ndikuwonetsedwa bwino m'maphunziro onse azinyama‍ ndi mayesero azachipatala a achinyamata omwe ali ndi vuto la kuzindikira chifukwa chovulala muubongo.

Pramiracetam imapangitsa kukumbukira bwino poyambitsa chidwi cha hippocampus, gawo laubongo lomwe limapangitsa kuti zikumbukiro zatsopano zizikhala komanso kukhala ngati anti anti amnesic yomwe imachepetsa kuiwala.Izi zimapangitsa kuti pramiracetam ikhale yolimbikitsa kukumbukira. Ogwiritsa ntchito ambiri amafotokozanso zakusintha kwakanthawi pakukumbukira kuthamanga, zomwe akuti zakhala zikugwirizana ndi maphunziro azinyama

• Kuzindikira Kowonjezereka ndi Kuwonjezera Kuphunzira Kuphunzira

Mbiri ya Pramiracetam monga chizolowezi chazidziwitso chomwe chimapangitsa kukhala watcheru ndikuwonjezera mphamvu zophunzirira chapangitsa kuti chisankhidwe pakati pa ophunzira omwe akufuna thandizo lodalirika pophunzira.

Ngakhale palibe kafukufuku waumunthu pazinthu izi zomwe zalembedwa, kafukufuku wazinyama akuwonetsa kuti pramiracetam imathandizira pakuwongolera kuphunzira ndi kukumbukira kukumbukira powonjezera zochitika za neuronal mtundu wa nitric oxide synthase (NOS) mu hippocampus. Ntchito ya NOS imalumikizidwa ndi chitukuko cha ubongo ndi ubongo mapulasitiki, onse omwe ndiofunikira pazinthu zonse zakuzindikira.

Pramiracetam imadziwikanso kuti imakulitsa kuchuluka kwa choline mu hippocampus, zomwe zimapangitsa kuti acetylcholine, neurotransmitter yofunika kwambiri yomwe imagwirizana kwambiri ndi kuphunzira komanso kuzindikira.

• Kuchiza kwa Dementia

Mayeso otseguka kwa odwala omwe ali ndi vuto lofooka poyambira amawonetsa kuti Pramiracetam idasinthiratu amnesia, kukulitsa kukumbukira ndikuchepetsa kuiwala.

M'maphunziro ena, omwe amayesa zovuta za pramiracetam ndi ma nootropics ena a racetam kwa odwala omwe ali ndi vuto la matenda amisala pang'ono, panali kusintha kosazindikirika pakumvetsetsa komanso kukumbukira. Zotsatirazi zikuyenera kufotokozedwa, mwina pang'ono, kukulitsa kwa nootropic kwa ma neurotransmitters omwe alipo.

Ngakhale pramiracetam sinavomerezedwe ngati mankhwala a Alzheimer ku US, nthawi zambiri amapatsidwa ku Europe kuti athe kuchiza matenda amisala ndi zovuta zina zokhudzana ndi matenda a Alzheimer's ndi matenda ena amitsempha.

• Kusintha kwa Pagulu

Ngakhale palibe kafukufuku wolemba za momwe pramiracetam imathandizira pakukhala bwino pagulu, ogwiritsa ntchito ambiri akuti zimawapangitsa kuti azitha kuyankhulana bwino komanso kucheza bwino. Izi zitha kufotokozedwa, mwina pang'ono, ndi pramiracetam yomwe imadziwika kuti idasokoneza malingaliro, yomwe nthawi zina imafotokozedwa kuti ndi yofanana ndi ya Ritalin. Izi zimachepetsa nkhawa zamagulu, kenako zimathandizira kuti anthu azikhala bwino.

• Mphamvu za Neuroprotective

Pramiracetam imadziwika kuti imakhala ndi zotupa zambiri za neuroprotectant, zomwe zimatha kukonza kuzindikira kwa anthu omwe adakumana ndi vuto laubongo.

Kafukufuku adawonetsanso kuti imawoneka ngati yothandizidwa ndi ma neuroprotective mukamagwiritsidwa ntchito panthawi yopanga opaleshoni komanso pochiza zovuta zamaganizidwe am'magazi.

Pramiracetam Mlingo wa Reference

Pramiracetam nthawi zambiri imabwera ngati ufa, makapisozi opangidwa kale, kapena mapiritsi. Ogwiritsa ntchito ena anena kuti mawonekedwe a ufa ali ndi kulawa kosasangalatsa, chifukwa chake amakonda kugwiritsa ntchito kapisozi kapena mawonekedwe apiritsi m'malo mwake.

Malinga ndi ofufuza ena, mitundu ya ufa ndi kapisozi imatha kukhala ndi mayamwidwe othamanga kwambiri kuposa mawonekedwe apiritsi. Komabe, mphamvu zonse komanso kuchita bwino kwake kumakhulupirira kuti ndikofanana pafupifupi mitundu yonse.

M'modzi mwayeso ochepa omwe achitika mpaka pano, kuchuluka kwa 1,200 mg kunagwiritsidwa ntchito, kugawidwa m'magulu awiri a 600-mg kapena atatu 400-mg omwe amafalikira tsiku lonse.

Monga membala wa banja la racetam la mankhwala osokoneza bongo, pramiracetam imakhulupirira kuti imadalira choline pazotsatira zake, ndipo kuyigwiritsa ntchito kumatha kuthetsa choline cha thupi. Pachifukwa ichi, nthawi zina amalimbikitsidwa kuphatikiza ma racetams ndi gwero la choline, monga alpha-GPC kapena citicoline. Komabe, malingalirowa amangotengera kafukufuku wa nyama imodzi, chifukwa chake izi siziyenera kutanthauziridwa kuti ndi lingaliro la "ovomerezeka" kapena "ovomerezedwa ndi zamankhwala".

Chidziwitso Chofunika: Pramiracetam okwana

Pramiracetam imagwira ntchito payokha koma itha kukhala othandiza kwambiri ku ma nootropics ena, kukulitsa mphamvu zawo.Ndi chida chothandiza kwambiri pamipikisano ina, ndikupangitsa kuti ikhale yowonjezerapo mwambiri nootropic mapaki.

Kuwonjezera choline kuwonjezera ku pramiracetam stack ikhoza kukhala ndi maubwino angapo. Sikuti imangolimbikitsa zotsatira za pramiracetam, komanso imatha kupewetsa mutu, womwe ndiwofala kwambiri. Chifukwa pramiracetam imakhala ndi zotulukapo zoterezi, ndibwino kuti muziigwiritsa ntchito yokha nthawi yoyeserera musanayiphatikize ndi ma nootropics ena .

Zitsanzo za 2 za Pramiracetam kupaka:

❶ Pramiracetam ndi Oxiracetam Stack

Stacking pramiracetam yokhala ndi zowonjezera mphamvu monga adrafinil kapena oxiracetam imatha kukulitsa chidwi cham'maganizo ndikuchiwonjezera nthawi yayitali.

RamPramiracetam ndi Aniracetam Stack

Stacking pramiracetam yokhala ndi chida champhamvu chotsutsa nkhawa monga aniracetam imatha kupatsa ogwiritsa ntchito chidwi ndikuwongolera pomwe akusintha malingaliro ndikuchepetsa nkhawa zamavuto. Ogwiritsa ntchito ena amati mulu uwu umalimbikitsa kusadukizana pakati pa anthu ndikuwongolera magwiridwe antchito pagulu.

Zotsatira Zotsatira za Pramiracetam

Pramiracetam nthawi zambiri imaloledwa ngakhale pamiyeso yayikulu, ndipo ndi zovuta zochepa zoyipa zomwe zalembedwa.

Pali malipoti omwe amapezeka pafupipafupi okhudzana ndi zovuta zazing'ono komanso zakanthawi, kuphatikiza kupweteka mutu, kupweteka m'mimba, komanso mantha kapena kusakhazikika. ‍ Nthawi zambiri, zoyipa zimayenderana ndi kuchuluka kwambiri ndipo zimatha kupewedwa pochepetsa kuchuluka komwe kumamwa.

Mutu womwe umakhudzana ndi kuchepa kwa choline ndi gawo loyipa la racetam mtundu wa nootropics ndipo limatha kupewedwa potenga pramiracetam molumikizana ndi choline chowonjezera.

Pramiracetam siyowonjezera, ndipo palibe zovuta zoyipa zakugwiritsa ntchito kwakanthawi zomwe zalembedwa. Pali umboni kuti pramiracetam imatha kulimbikitsanso thanzi laubongo komanso kubwezeretsanso ntchito muubongo wokalamba.

Kodi Malo Ogula Abwino Ali Kuti? Pramiracetam Online? 

Ngakhale ndizowona kuti Piracetam ndi imodzi mwama nootropics olonjeza kwambiri, imangokhala ndi maphunziro ochepa azachipatala ndipo ambiri a iwo, ngati sanatchulidwe, ndi maphunziro ofufuza nyama ndi zina.Choyerekeza, ndizochepa poyerekeza ndi zina za nootropics koma thanzi lake lina Ndizothandiza kwambiri kwa achikulire omwe ali ndi vuto la m'maganizo koma amalimbikitsidwanso kuti atengeredwe ndi ana komanso achikulire okhudzana ndi zosowa zawo. nootropics.

Pali malo ambiri omwe ali ndi Piracetam yogulitsa pa intaneti. Komabe, ndibwino kugula kuchokera pa webusayiti yomwe ikukwaniritsa miyezo yabwino pamundawu. AASraw ndiwodalirika wopereka ma nootropics, malonda awo onse amapangidwa pansi pa cGMP ndipo mtunduwo umatha kutsatidwa nthawi iliyonse, monga tikudziwira. Mutha kuganizira za iwo ngati mukufuna kugula Pramiracetam powder.

Zitha kugulidwa bwino kwa wogulitsa uyu. Amagulitsa mankhwala odalirika ndi CoA ndipo amatumiza padziko lonse lapansi. Monga mankhwala ena aliwonse, masitolo ena angafunike mankhwala musanagule. Mitengo ya Piracetam imasiyananso kutengera komwe kuli.

Reference

[1] Ogwira Ntchito, Pepala Lapinki. Meyi 27, 1991 Cambridge Neuroscience Kupanga Pramiracetam ya Warner-Lambert

[2] FDA Orphan Drug Designation and Approvals Database Tsamba lidafika pa Ogasiti 2, 2015

[3] Drugs.com Drugs.com Mndandanda wapadziko lonse wa pramiracetam Tsamba lidafika pa Ogasiti 2, 2015

[4] Auteri et. al. Magazini yapadziko lonse lapansi yokhudza kafukufuku wamankhwala azachipatala, 12 (3), 129-132 (1992-1-1)

[5] Zomwe zimachitika pakugwiritsa ntchito pramistar, kukonzekera kwatsopano kwa nootropic, pochiza zovuta zam'mimba mwa odwala omwe ali ndi matenda am'magazi. 2003 Dec.

[6] Kugwiritsa ntchito nootropic wothandizila othandizira odwala omwe ali ndi vuto laubongo. 2008 Meyi 30.