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Trilostane Powder (13647-35-3)

mlingo: SKU: 13647-35-3. Category:

AASraw ali ndi kaphatikizidwe ndi kutulutsa mphamvu kuchokera pa gramu kupita ku misa ya Trilostane Powder (13647-35-3), motsogozedwa ndi CGMP ndikuwongolera dongosolo loyang'anira.

Mafotokozedwe Akatundu

Trilostane Powder (13647-35-3) kanema


Trilostane Powder (13647-35-3) Specification:

Kapangidwe ka Chemical: Name mankhwala: Trilostane
Mlandu.: 13647-35-3
Molecular Formula: C20H27NO3
Kulemera kwa maselo: 329.43
Standard: Kunyumba
Kusungirako: Dry, mdima ndi 0 - 4 C kwa nthawi yochepa (masiku mpaka masabata) kapena -20 C kwa nthawi yaitali (miyezi mpaka zaka).
Zolemba (COA & HPLC etc.): Mukhozanso

Trilostane Powder (13647-35-3) Dkulemba:

Trilostane ufa ndi choletsa wa 3β-hydroxysteroid dehydrogenase yomwe imagwiritsidwa ntchito pochiza matenda a Cushing's syndrome ndi hyperaldosteronism yoyamba. Awa ndi mavuto onse omwe mahomoni ochulukirapo a corticosteroid amapangidwa m'thupi. Corticosteroids ndikofunikira kuti thupi lizigwiritsa ntchito chakudya, mafuta ndi mapuloteni komanso poyankha yachilendo pakakhala kupsinjika. Ndizofunikira pakuwongolera mchere ndi madzi olimbitsa mthupi. Trilostane ufa amathandizira kupewa kupanga corticosteroids, kuwongolera zizindikiro zomwe zimagwirizanitsidwa ndi izi.

Trilostane ufa amathanso kuthandizika pakuthandiza khansa ya m'mawere yomwe yabwereranso mwa azimayi omwe adasiya kusamba.

Idavomerezedwa posachedwa mu 2008 pochiza matenda a Cushing (hyperandrenocorticism) mu agalu. Ndiwonso woyamba mankhwala kuvomereza onse pituitary- ndi adrenal-amadalira Cushing a agalu. Mankhwala othandizira awa amagwira ntchito poletsa kupanga kwa cortisol mu grenisol.

Tsamba:

  • 1: Midence JN, Drobatz KJ, Hess RS. Cortisol Concentrations mu Agalu Olamulidwa bwino omwe ali ndi Hyperadrenocorticism Zochitika ndi Trilostane. J Vet Intern Med. 2015 Nov; 29 (6): 1529-33. doi: 10.1111 / jvim.13615. Epub 2015 Sep 16. PubMed PMID: 26374943.
  • 2: Fracassi F, Corradini S, Floriano D, Boari A, Aste G, Pietra M, Bergamini PF, Dondi F. Practostic zinthu zopulumuka mu agalu okhala ndi hypercortisolism yodalira pituirs. Vet Rec. 2015 Jan 10; 176 (2): 49. doi: 10.1136 / vr.102546. Epub 2014 Aug 28. PubMed PMID: 25170036.
  • 3: Bonadio CM, Feldman EC, Cohen TA, Kass PH. Kuyerekeza kwa adrenocorticotropic timadzi timene timayambitsa zotsatira zinayambira 2 patatha maola 4 pambuyo pa utsogoleri wa trilostane mu agalu omwe amakhala ndi hyperadrenocorticism yachilengedwe. J Vet Intern Med. 2014 Jul-Aug; 28 (4): 1239-43. doi: 10.1111 / jvim.12357. Epub 2014 Meyi 26. PubMed PMID: 24863172.

KULAMBIRA NDI KUSINTHA:

Nkhaniyi Ikagulitsidwa Kugwiritsa Ntchito Kafukufuku kokha. Migwirizano Yogulitsa. Osati Zongogwiritsa Ntchito Anthu, kapena Zamankhwala, Zoweta Zanyama, kapena Zogwiritsa Ntchito Panyumba.


COA

HNMR

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