Mafotokozedwe Akatundu
Alpha GPC Powder Video-AASraw
Makhalidwe Oyambira a Alpha GPC Powder
| Name: | Alpha GPC ufa |
| CAS: | 28319-77-9 |
| Maselo chilinganizo: | C8H20NO6P |
| Kulemera kwa Maselo: | 257.22 |
| Melt Point: | 142.5-143 ° |
| Kusungirako nyengo: | -20 ° C |
| mtundu; | White powder |
Kodi Alpha GPC Powder ndi chiyani?
Alpha GPC, yomwe imadziwikanso kuti Alpha-glycerophosphocholine (aGPC), ndi phospholipid yokhala ndi choline yochokera ku soya. Kafukufuku wosiyanasiyana pamankhwalawa akuwonetsa gawo pakuwongolera magwiridwe antchito anzeru, kulimbikitsa mphamvu, komanso kuyambitsa kupanga kwa mahomoni okula.
AASraw's Alpha GPC Powder ndi chida chothandiza kwambiri chothandizira kukumbukira ndi kuphunzira, komanso kuthana ndi kuchepa kwa chidziwitso ndi zizindikiro za matenda a Alzheimer's. Pamene wodwala akuwonetsa zizindikiro za kuchepa kwa chidziwitso, zomwe nthawi zina zimatchedwa "Brain Fog," Alpha GPC supplementation zimathandiza kuganiza momveka bwino komanso momveka bwino. Gwero labwino kwambiri la choline lingagwiritsidwenso ntchito ndi anthu athanzi kuti awonjezere chidziwitso. Chiwindi ndi nyama zina za chiwalo, zomwe sizikhalanso nthawi zambiri muzakudya zaku North America, ndizo zakudya zokhala ndi choline kwambiri. Zotsatira zake, tazindikira kuti anthu ambiri ndi opereŵera ndipo akhoza kupindula kwambiri powonjezera ndi Alpha GPC. Ndi gwero labwino lamafuta ogwirira ntchito za ubongo. Tsiku lonse, anthu ambiri amavutika ndi mphamvu komanso kuganizira kwambiri. Chotsatira chake, anthu ambiri akuyang'ana njira yothetsera vuto la masana kuti athe kuwongolera maganizo awo. Alpha GPC ufa kuchokera ku AASraw ndi chowonjezera chomwe chimathandiza ndi kuganizira zamaganizo ndi ntchito.
Pitilizani kuwerenga kuti mudziwe momwe Alpha GPC imagwirira ntchito, zabwino zake ndi zoopsa zomwe zingachitike, komanso mlingo.
Kodi Alpha GPC Powder imagwira ntchito bwanji pathupi?
Alpha GPC ufa umagwira ntchito pokweza ma acetylcholine (ACh) mu ubongo. Acetylcholine ndi neurotransmitter yomwe imagwira ntchito pakupanga kukumbukira ndi kuphunzira, komanso kuchepa kwa minofu.
Matupi athu amapanga acetylcholine wocheperako komanso wocheperako tikamakalamba. Izi zitha kubweretsa zovuta za kukumbukira komanso kuwonongeka kwachidziwitso pang'ono. Alpha GPC ufa amaonedwa kuti amathandiza kupewa kuchepa kwa chidziwitso chokhudzana ndi ukalamba mwa kupititsa patsogolo ma acetylcholine mu ubongo ndikugwira ntchito ngati pro-cholinergic nootropic mankhwala. Izi zikutanthauza kuti imathandizira kupanga acetylcholine, yomwe ingathandize kukulitsa magwiridwe antchito amalingaliro.
Phosphatidylcholine (PC), chigawo chofunikira cha maselo a cell, ndizomwe zimayambira ufa wa Alpha GPC. PC ndiyofunikira pa thanzi komanso kusinthasintha kwa nembanemba zama cell. Zimathandiziranso kupanga mapangidwe a myelin sheath, chophimba chamafuta chomwe chimaphimba ndikuteteza ma neurons. Ubongo umapangidwa ndi mabiliyoni a neuroni omwe amatumiza ndi kulandira mphamvu zamagetsi nthawi zonse. Kuti ubongo wathu ugwire ntchito moyenera, mauthengawa ayenera kukhala ofulumira komanso ogwira mtima. Chophimba cha myelin chimagwira ntchito ngati insulator, kuteteza mitsempha ya mitsempha ndi kulola kuti zizindikiro zamagetsi ziziyenda mofulumira komanso moyenera.
Apa ndipamene Phosphatidylcholine (PC) imalowa. PC ndiyofunikira kuti zisungidwe zama cell athanzi komanso kuti pakhale chitukuko cha myelin sheath.
Imasinthidwa kukhala Alpha GPC kudzera m'njira ziwiri zosiyana:
Kennedy Pathway
Njira ya Methylation
Kennedy Pathway ndi njira zingapo zomwe zimapereka njira imodzi yofunika kwambiri pakuwongolera kukula kwa ma cell. Choline yaulere imasinthidwa kukhala cytidine diphosphate (CDP), yomwe pambuyo pake imalumikizidwa ndi diacylglycerol kuti ipange PC. Njira ya methylation imatembenuza PC, yomwe imapangidwa ndi phosphatidylethanolamine ndi choline, kukhala chofunikira kwambiri pakupanga kusungunula kwa myelin muubongo wanu. Ndi zochita za Phospholipase D, PC imasinthidwa kukhala 1-acyl-GPC kenako kukhala Alpha GPC. The Alpha GPC pambuyo pake imanyamulidwa kudutsa chotchinga chamagazi-ubongo, komwe imakweza milingo ya acetylcholine muubongo.
Kodi Ubwino Waumoyo wa Alpha GPC Ndi Chiyani?
· Alpha GPC ngati nootropic.
Anthu ambiri amagwiritsa ntchito Alpha GPC kukumbukira chifukwa maphunziro oyambira akuwonetsa kuti zitha kuthandiza pakuphunzira. AASraw Alpha GPC imawonjezera mapangidwe a acetylcholine, omwe ndi ofunikira kukumbukira ndi kuwongolera nzeru. Kafukufuku wina adayang'ana pa Alpha GPC kuti ayang'ane ndipo adawona kuti ndi yothandiza. Zotsatira zake, ufa wa Alpha GPC ukhoza kukhala wothandiza pakukulitsa chidwi.
· Alpha GPC ndi thanzi la mtima.
Miyezo ya homocysteine imakwera mukadya nyama yambiri. Miyezo ya homocysteine yokwera kwambiri imatha kukhala ndi zotsatira zovulaza paumoyo wamtima. Choline imathandizira kusintha kwa homocysteine ku methionine, amino acid yofunika kwambiri yomwe imathandiza mu protein biosynthesis. Kuphatikiza apo, kafukufuku wina adapeza kuti kudya kwa choline kwa nthawi yayitali kumathandizira kuchepetsa kutupa ndi zoopsa zina zomwe zimawononga thanzi la mtima. Ngakhale maphunziro owonjezera akufunika, Alpha GPC ikhoza kupindulitsa thanzi la mtima.
· Alpha GPC ndi kupsinjika.
Mukadya nyama yambiri, ma homocysteine amawonjezeka. Mulingo wopanda thanzi wa homocysteine ukhoza kuwononga thanzi la mtima. Homocysteine amasinthidwa ndi choline kukhala methionine yofunika kwambiri ya amino acid, yomwe ndiyofunikira pakupanga mapuloteni. Kuphatikiza apo, kafukufuku wina adapeza kuti kumwa kwa choline kosatha kumachepetsa kutupa ndi zoopsa zina ku thanzi la mtima. Alpha GPC ikhoza kupititsa patsogolo thanzi la mtima, koma kufufuza kwina kumafunika.
· Alpha GPC ndi machitidwe a thupi.
Malinga ndi kafukufuku, Alpha GPC ndi njira yabwino kwambiri yopititsira patsogolo mphamvu zamagetsi ndi mahomoni omwe amalimbikitsa kukula kwa minofu. Malinga ndi kafukufuku wa 2015, omwe adatenga ufa wa Alpha GPC nthawi zonse adawona kuwonjezereka kwamphamvu kwa minofu pambuyo pa masiku 6. Pakufufuza kwina, ufa wa Alpha GPC unapezeka kuti umalimbikitsa kukula kwa hormone kupanga ndi okosijeni wamafuta mwa achinyamata athanzi. Hormone ya kukula kwaumunthu (HGH) imalimbikitsa kukula kwa minyewa, kuchepetsa mafuta, komanso kukonza minofu mwachangu.
(Njira ya Alpha GPC kukonza minofu)
Kodi pali chiwopsezo cha kuwonongeka kwakanthawi kotenga Alpha GPC?
Kafukufuku wasonyeza kuti Alpha GPC ilibe vuto lililonse pazigawo za magazi monga kuthamanga kwa magazi kapena kugunda kwa mtima. Mlingo wapamwamba wa Alpha GPC (1000 mg kapena kuposerapo) ungayambitse mutu kwa anthu ena mpaka kulekerera kwawo kwa zowonjezera kukhazikitsidwa. Mlingo wotsika kwambiri womwe anthuwa amayambira ndi 300 mg patsiku.
Kodi mumatenga bwanji Alpha GPC Powder?
Popeza Alpha GPC ili ndi pafupifupi 40% choline ndi kulemera kwake, 1,000 mg ya Alpha GPC ufa kuchokera ku AASraw imapereka pafupifupi 400 mg ya choline ya zakudya. Malinga ndi zomwe zimachitika pafupipafupi, mlingo wamba wa Alpha GPC ndi 300-600 mg. Ndalamayi mwina ndi mlingo woyenera kwa othamanga, chifukwa amatsatira kafukufuku wogwiritsa ntchito Alpha GPC kuti apititse patsogolo mphamvu (600 mg) ndi maphunziro awiriwa akuwonetsa kuwonjezeka kwa kukula kwa hormone.
Pafupifupi maphunziro onse amagwiritsa ntchito mlingo wa 1,200 mg tsiku lililonse, wogawidwa m'magulu atatu a 400 mg, kuti athetse zizindikiro za kuwonongeka kwa chidziwitso. Sizikudziwika kuti zing'onozing'ono zingathandizire bwanji kuzindikira, komabe mulingo womwe umawoneka kuti umagwirizana nthawi zonse ndi phindu ndi 1,200 mg. Malingana ndi maphunziro a makoswe, zotsatira za Alpha GPC pakamwa pakamwa zimafika pamtunda wa 300-600 mg / kg, zomwe zimafanana ndi mlingo wa anthu wa 48-96 mg / kg (ndi kwa 150lb munthu, 3,272-6,545 mg tsiku lililonse).
Kuti mugwiritse ntchito stack ya nootropic, timalimbikitsa kuyambira ndi 300-600 mg ndikuwonjezera pang'onopang'ono ngati mukumva kuti mungapindule ndi zambiri. Alpha GPC imaloledwa bwino ikatengedwa pamilingo yolembedwa. Mulingo woyenera wa mlingo wa anthu ambiri ndi waukulu; Mlingo watsiku ndi tsiku wa 300-1200 mg, woperekedwa mu Mlingo umodzi kapena iwiri, ndiwotetezeka komanso wothandiza.
Mofanana ndi zowonjezera zowonjezera, ndi bwino kuyamba ndi mlingo wotsika kwambiri wotheka ndikuwonjezera pang'onopang'ono ngati pakufunika.
Alpha GPC vs. CDP Choline
Tiyeni tiyambe ndi zoyambira. CDP choline, yomwe imadziwikanso kuti citicoline, imapangidwa ndi choline (magulu awiri a phosphate) ndi cytidine, pamene Alpha GPC imapangidwa ndi choline (gulu limodzi la phosphate) ndi glycerol. Izi zingawoneke ngati zofanana, komabe zimapanga zinthu zina zochititsa chidwi ndi zosiyana m'thupi.
Chifukwa chimodzi, Alpha GPC imakweza milingo ya choline yamagazi kuposa CDP choline. Zotsatira zake, zimakhala ndi chikoka champhamvu pakuchepa kwachidziwitso chokhudzana ndi zaka komanso magwiridwe antchito athupi. Chachiwiri, Alpha GPC ikhoza kulimbikitsa kutentha kwa mafuta ndi mbadwo wa kukula kwa hormone, kupereka mwayi woposa CDP choline mu omanga thupi.
CDP choline, kumbali ina, imayenera kupanga phosphatidylcholine. Imakhala ndi ma metabolites ochulukirapo ndipo imatha kukhala ndi thanzi labwino m'maganizo.
Kodi mungagule kuti Alpha GPC Powder?
N’zosavuta kuiwala kuti thupi lanu limagwira ntchito ngati makina. Pankhani yoyendetsa makina, pamafunika mafuta oyenera, omwe ndi ofunikira kwambiri ngati muli otakataka. Ndi zakudya ziti zomwe muyenera kudya kuti muwonjezere kulimbitsa thupi kwanu? Ndipo izi zidzachitika liti?
Chonde kumbukirani kuti si anthu onse omwe amapindula ndi Alpha GPC Powder. Mwinamwake munagula Powder yoipa ya Alpha GPC ndilo lingaliro loyamba, momwe mungapezere weniweni Alpha GPC Powder wopanga, muyenera kutaya zoyesayesa zanu pa izo. Ngati mumagula ufa wa Alpha GPC kuchokera ku AASraw, mudzapeza mtengo wabwino wa Alpha GPC Powder.
Zowonjezera zonse kuchokera kwa wothandizira AASraw amapangidwa ndikuyesedwa kuti atetezedwe ndi khalidwe labwino, kuonetsetsa kuti zowonjezera zowonjezera zimaperekedwa kwa inu. Alpha GPC ufa ukhoza kusungidwa mochuluka pa AASraw pazogulitsa zogulitsa.
Raw Alpha GPC Powder Testing Report-HNMR
Kodi HNMR ndi chiyani ndipo HNMR sipekitiramu imakuuzani chiyani? H Nuclear Magnetic Resonance (NMR) spectroscopy ndi njira yowunikira ya chemistry yomwe imagwiritsidwa ntchito poyang'anira zabwino ndi kafukufuku kuti adziwe zomwe zili ndi kuyera kwa sampuli komanso kapangidwe kake ka maselo. Mwachitsanzo, NMR imatha kusanthula mochulukira zosakaniza zomwe zili ndi mankhwala odziwika. Pazinthu zosadziwika, NMR itha kugwiritsidwa ntchito kuti ifanane ndi malaibulale owoneka bwino kapena kutsimikizira kapangidwe kake mwachindunji. Mapangidwe oyambira akadziwika, NMR itha kugwiritsidwa ntchito kudziwa momwe mamolekyulu amathandizira komanso kuphunzira zakuthupi pamlingo wa maselo monga kusinthana kosinthika, kusintha kwa magawo, kusungunuka, ndi kufalikira.
Alpha-GPC(28319-77-9)-COA
Kodi mungagule bwanji Alpha GPC Powder kuchokera ku AASraw?
❶Kuti mutitumizire kudzera pa imelo yathu yofunsira, kapena kutisiyira nambala yanu ya whatsapp, woimira makasitomala athu (CSR) azilumikizana nanu m'maola 12.
❷Kutipatsirani kuchuluka kwanu ndi adilesi yomwe mwafunsidwa.
❸CSR yathu idzakupatsani nthawi yowerengera, nthawi yolipira, nambala yotsatirira, njira zobweretsera komanso tsiku loti mudzafike (ETA).
❹Ndalipira ndipo katundu adzatumizidwa mkati mwa maola 12.
❺Katundu wolandilidwa ndi kupereka ndemanga.
Wolemba nkhaniyi:
Dr. Monique Hong adamaliza maphunziro awo ku UK Imperial College London Faculty of Medicine
Scientific Journal paper Wolemba:
1. CC Carson
Dipatimenti ya Opaleshoni, Division of Urology, University of North Carolina, Chapel Hill, NC,
2. I. Eardley
Chipatala cha St. James' University, Leeds, UK,
3. DJ Walker
Eli Lilly and Company, Indianapolis, IN, USA
4. WH Cordell
Eli Lilly and Company, Indianapolis, IN, USA
Dokotala/wasayansiyu savomereza kapena kulimbikitsa kugula, kugulitsa, kapena kugwiritsa ntchito mankhwalawa pazifukwa zilizonse. Aasraw alibe chiyanjano kapena ubale, wonenedwa kapena ayi, ndi dokotala uyu. Cholinga chotchula dokotalayu ndikuvomereza, kuvomereza ndi kuyamika ntchito yofufuza ndi chitukuko yomwe asayansi akugwira ntchitoyi.
Reference
[1] De Jesus Moreno Moreno M (Januware 2003). "Kusintha kwachidziwitso kwa dementia wofatsa mpaka wocheperako wa Alzheimer's pambuyo pa chithandizo ndi acetylcholine precursor choline alfoscerate: kuyesa kosiyanasiyana, kopanda khungu, kosasinthika, koyendetsedwa ndi placebo". Clinical Therapeutics. 25 (1): 178-93. PMID 12637119.
[2] Parnetti L, Mignini F, Tomassoni D, Traini E, Amenta F (June 2007). "Cholinergic precursors pochiza kuwonongeka kwa chidziwitso cha chiyambi cha mitsempha: njira zosagwira ntchito kapena kufunikira kowunikanso?". Journal of the Neurological Sciences. 257 (1–2): 264–9. Chithunzi cha PMID 17331541.
[3] Doggrell SA, Evans S (October 2003). "Kuchiza kwa dementia ndi neurotransmission modulation". Malingaliro a Akatswiri pa Mankhwala Ofufuza. 12 ( 10 ): 1633-54 . Mtengo wa PMID 14519085.
[4] Wallace, TC et al. (2019). Choline: Chofunikira cha Neurocognitive Chofunikira kwa Obstetricians ndi Gynecologists. Journal of Dietary Supplements, 17 (6), pp.733-752.
[5] Moreno, M. (2003). Kusintha kwachidziwitso kwa dementia wofatsa mpaka wocheperako wa Alzheimer's pambuyo pa chithandizo ndi acetylcholine precursor choline alfoscerate: kuyesa kosiyanasiyana, kopanda khungu, kosasinthika, koyendetsedwa ndi placebo. Clinical Therapeutics, [pa intaneti] 25 (1), pp.178-193.
