Gulani fakitole yoyamba ya ufa wa CBD & mafuta opanga mafuta
AASraw imapanga ufa wa Cannabidiol (CBD) ndi Hemp Mafuta Ofunika ambiri!
CBD yatenga chidwi posachedwa, makamaka pakati pa achinyamata. Pafupifupi 20% ya anthu azaka zapakati pa 18 ndi 29 zaka amagwiritsa ntchito mtundu wina wa CBD, pomwe 8% yokha ya anthu azaka zopitilira 65 amagwiritsa ntchito CBD. Anthu azaka zapakati nawonso ayamba kupeza anthu ocheperako ndipo pafupifupi 30 peresenti ya m'badwo uno amadya mowa wa CBD, kaya ndi mafuta, ufa, kapena mawonekedwe opopera.

Ogwiritsa ntchito ambiri amati amagwiritsa ntchito mankhwalawa kuti athe kuthana ndi ululu ndikuchepetsa zizindikilo za nkhawa ndi zovuta zina zonga nkhawa. Kugwiritsiridwa ntchito kwa CBD kudakulanso pambuyo poti chamba chalamulo chasintha, zomwe sizofanana ndi CBD. Komabe, kuvomereza chamba mwalamulo kunathandiza kuchotsa manyazi omwe amagwiritsidwa ntchito komanso kugwiritsa ntchito mankhwala osokoneza bongo omwe amapezeka mchomeracho.

Kodi N'chiyani? CBD (Cannabidiol)?

Cannabidiol kapena CBD ndi phytocannabinoid yomwe imachokera kuzomera za cannabis ndipo ndi imodzi mwazinthu zazikuluzikulu za chamba, ndi chomera cha msuwani wawo, hemp yomwe imawapatsa mavuto. Ndikofunika kuzindikira kuti cannabidiol imachokera ku chomera cha hemp, chomwe chili m'gulu lazomera za cannabis koma sizomwe zimatchedwa chamba. Momwe imachokera ku chomera cha hemp, ilibe zida zilizonse zama psycheactive kutanthauza kuti sizingapangitse anthu kukhala 'okwera'.

Chomera cha cannabis sativa, makamaka, chamba chimatha kupangitsa anthu kudzimva chifukwa cha Delta-9-tetrahydrocannabinol kapena THC, phytocannabinoid ina yochokera kuzomera za cannabis. Chamba chimakhala ndi THC yochulukirapo kuposa mitundu ina ya chamba monga hemp ndichifukwa chake ili ndi zida zamagetsi pakati pazomera zina zonse. CBD imachokera ku chomera cha hemp chomwe chili ndi CBD yambiri koma chili ndi THC yocheperako, ndikupangitsa kuti ikhale njira yabwino kwambiri kwa anthu omwe angafune kupindula ndi chomera cha Cannabis sativa popanda zovuta zamaganizidwe.

Zotsatira za CBD ndi THC ndizofanana poganiza kuti zonsezi zimakhudza mankhwala osiyanasiyana kapena ma neurotransmitters muubongo koma gulu lililonse la cannabinoid limakhudza mankhwala osiyanasiyana ndipo limakhudza mosiyanasiyana, motero limabweretsa zotsatira zosiyana.

Cannabidiol idapezeka koyamba mu 1940 ngati phytocannabinoid yopanda psychoactive m'mitengo ya cannabis koma mpaka 2018 pomwe USA idachotsa, pamodzi ndi chomera cha kholo, hemp, kuchokera ku Mndandanda Wazinthu Zoyendetsedwa. Komabe, ndizosaloledwa kuti anthu azigwiritsa ntchito ufa wa cannabidiol, mafuta a CBD, kapena zinthu zina za CBD mwanjira zawo zoyera kapena kapangidwe kalikonse ngati mankhwala kapena chida chowonjezera pazakudya.

Mankhwala a CBD amavomerezedwa ndi Food and Drug Administration kapena FDA ku United States of America kuti athe kuchiza khunyu ndi matenda a khunyu. Ndikulimbikitsidwanso pazinthu zina zamankhwala, komabe, apezabe kuvomerezedwa ndi a FDA ndi mayiko ena asadakhale osamalidwa.

Kodi CBD imagwira ntchito bwanji pa thupi?

M'malo mwake, akatswiri akhala akukambirana mutu wakuti "CBD imagwira ntchito bwanji m'thupi la munthu" kwazaka zambiri. Zikuwoneka kuti mfundo zotsutsana zapezeka. Asayansi amakhulupirira kuti CBD imagwira ntchito molakwika pa dongosolo la endocannabinoid kuti lipindule. Tisanamvetsetse momwe CBD imagwirira ntchito pathupi lathu, tiyenera kumvetsetsa kachitidwe kake ka endocannabinoid ndipo kamakhala bwanji mthupi lathu?

Kodi Endocannabinoid System (ECS) ndi chiyani?

"Cannabinoid" imachokera ku "cannabis," ndipo "endo" ndichidule kwa "amkati," zomwe zikutanthauza kuti amapangidwa mwachilengedwe mkati mwa thupi lanu. Chifukwa chake "endocannabinoid" amangotanthauza zinthu ngati zachamba zomwe mwachilengedwe zimachitika mkati mwathu.

ECS yokha ili ndi magawo atatu:
① Endocannabinoids
Olandira (CB1, CB2) mumanjenje ndi kuzungulira thupi lanu komwe ma endocannabinoids ndi cannabinoids amalumikizana nawo. (Ma CB1 receptors amapezeka mthupi lonse, makamaka muubongo. Amagwirizanitsa kayendedwe, kupweteka, kutengeka, malingaliro, kulingalira, kudya, kukumbukira, ndi ntchito zina . Ma CB2 receptors ndiofala kwambiri m'thupi. Zimakhudza kutupa ndi kupweteka)
③ Mavitamini omwe amathandiza kuthetsa endocannabinoids ndi cannabinoids

Sikuti ECS ndi gawo lachilengedwe la matupi athu okha, komanso ndichofunikira kwambiri. Endocannabinoid system (ECS) imachita gawo losangalatsa komanso losiyanasiyana mthupi. Pazofunikira kwambiri, dongosolo la endocannabinoid ndi netiweki yayikulu yama cannabinoid receptors yomwe imafalikira mthupi lonse. Dongosolo la endocannabinoid laumunthu limatulutsa ma cannabinoids omwe amalumikizana ndi zolandilira zomwe zimapezeka munyama zathupi zathu. Muthanso kutenga phyto-cannabinoids (CBD) kuphatikiza pa zinthu zomwe thupi lanu limapanga kuti zithandizire kukulitsa dongosolo lino. Udindo wa endocannabinoid system ndikubweretsa kuthupi lathu, kuphatikizapo mtima, kugaya chakudya, endocrine, chitetezo chamthupi, mantha, komanso njira zoberekera. Mwachidule, ikugwira ntchito kuti musalowerere ndale. Kusalowerera ndale kumatanthauza zinthu zosiyanasiyana m'malo osiyanasiyana mthupi lanu, chomwe mwina ndichimodzi mwazinthu zabwino kwambiri pamakinawo - zimatha kusintha zolandila zosiyanasiyana m'thupi lanu.

Mosiyana ndi izi, CBD siyopanda chidwi, siyingakulamulireni ndikupangitsani kuti musiye kugwiritsa ntchito mankhwala a CBD kapena CBD. CBD sasintha malingaliro amunthu akagwiritsa ntchito. Komabe, zitha kubweretsa kusintha kwakukuru mthupi, ndipo zikuwonetsa zabwino zina zamankhwala.



Asayansi kale ankakhulupirira kuti CBD imagwirizanitsidwa ndi zolandilira za CB2, koma kafukufuku watsopano wasonyeza kuti CBD silingagwirizane ndi cholandilira chilichonse. M'malo mwake, amakhulupirira kuti CBD imakhudza dongosolo la endocannabinoid mwachindunji. Zotsatira za CBD Pazakudya Zosagwirizana ndi Endocannabinoid Munthu wina akatenga CBD, mankhwalawa amalowa m'dongosolo lanu komanso ku endocannabinoid system (ECS). Popeza kuti cannabidiol yapezeka kuti ilibe mgwirizano wogwirizana, asayansi amakhulupirira kuti maubwino amtundu wa CBD amapangidwa kudzera zochita zina.

CBD imaletsa mafuta acid amide hydrolase (FAAH), omwe amawononga anandamide ndikufooketsa. CBD imafooketsa FAAH, zomwe zimabweretsa kuchuluka kwa anandamide. Anandamide amadziwika kuti "molekyulu yamtendere" ndipo amatenga gawo lofunikira pakukhala kosangalatsa komanso kolimbikitsa. Kuwonjezeka kwa anandamide kumatha kukhala ndi zotsatira zabwino pamakina a endocannabinoid.

CBD imakhudzanso mafuta omanga mapuloteni (FABP). Mapuloteni a FABP amamanga anandamide ndikusamutsa enzyme kunja kwa synapse kuti iwonongeke ndikukhala ndi FAAH. CBD imakhudza mayendedwe a FABP kuti anandamide yocheperako isakanike, ndikupanganso kuchuluka kwa anandamide.

Pomaliza, CBD imadziphatika ku G-protein receptors yotchedwa TRPV-1. Ma TRVP-1 receptors amathandizira kuthana ndi ululu, kutentha thupi, ndi kutupa. Ndi kudzera pachimango ichi pomwe asayansi amakhulupirira kuti CBD imathandizira pakatupa komanso kupumula kupweteka.

Mwachidule, dongosolo la endocannabinoid limathandizira kuti thupi lizikhala homeostasis. Mukamwa, Cannabidiol Zitha kuthandiza kukhathamiritsa matupi athu kuti azigwira ntchito bwino. CBD imagwirizana ndi ma cannabinoid, dopamine, opioid ndi serotonin receptors m'matupi mwathu, kenako ikwaniritsa ntchito zambiri zathupi lathu.

Ubwino Wathanzi la CBD

Kutchuka ndi kutchuka kwa CBD kumatha kukhala chifukwa cha maubwino osiyanasiyana omwe ali nawo mthupi la munthu, ambiri omwe samangofufuzidwa kokha koma chifukwa cha kafukufukuyu, mothandizidwa ndi umboni wasayansi. Asanakhazikitsidwe ndikugwiritsidwa ntchito kwakukulu kwa kampaniyo, mitundu ingapo ya kafukufuku idachitidwa kuti ingophunzira momwe mungagwiritsire ntchito phindu la CBD komanso kupenda ndikuwunika chitetezo ndi kuwopsa kwa poizoni wa kampaniyo.

Maubwino ambiri a CBD atchulidwa pansipa, komanso maphunziro osiyanasiyana omwe atsimikizira izi.

Management Kusamalira Zowawa ndi Kupumula

Anthu ambiri amakonda kugwiritsa ntchito CBD kuti athandizidwe makamaka. Pali zolemba za chamba zomwe zimagwiritsidwa ntchito ngati mankhwala opha ululu, kuyambira 2900 BC. Zomera za cannabis zitha kukhala ngati mankhwala othetsa ululu komanso zimathandizira kupweteka kwamtundu wina chifukwa chakuchita kwawo pa cholandilira cha cannabinoid mthupi.

Thupi la munthu limakhala ndi endocannabinoid system kapena ECS m'malo mwake yothandizira pazinthu zingapo zofunika monga kugona, njala, komanso kuyankha mthupi. ECS ndi yomwe imayambitsa kumasulidwa kwa ma cannabinoids amkati omwe amagwira ntchito yolandila cannabinoid ndikuchepetsa ululu, kumawonjezera chitetezo cha mthupi, kumapangitsa njala ndi kugona. CBD ndi THC zonsezi ndi ma cannabinoids omwe akamwedwa pakamwa kapena pamutu, amalumikizana ndikumangiriza ndi ma cannabinoid receptors. Popeza izi zowoneka bwino cannabinoids ndizofanana ndi zamkati cannabinoids, atha kupanga zotsatira zofananira ndi zamkati, ngakhale zotsatira zawo zitha kukhala zokokomeza pang'ono.

Mu 2018, ofufuza adachita meta-kusanthula mabuku onse omwe adasindikizidwa mpaka 2017 pazabwino za ntchito ya cannabidiol mwa odwala omwe ali ndi ululu wa m'mapapo chifukwa cha matenda oyipa. Maphunziro khumi ndi asanu ndi atatu mwa khumi ndi asanu ndi atatu omwe adachita nawo kafukufukuyu adapeza kuti odwala ambiri amamasulidwa kuzowawa atatenga 27mg THC ndi 25 mg CBD.

Kuphatikiza apo, maphunziro onse adapeza kuti zoyipa zoyipa kwambiri pakuphatikizaku zinali nseru, pakamwa pouma, ndi kusanza. Zotsatirazi sizinapezeke mwa wodwala aliyense ndipo omwe akhudzidwa sanakhale ndi vuto lokwanira. Izi zidapangitsa kuti ofufuza aganizire kuti kugwiritsa ntchito kwa THC ndi CBD, kumatha kuthana ndi ululu wa m'mitsempha ndipo kumalekerera ndi chiopsezo chochepa chazovuta.

Pali mitundu yambiri ya kafukufuku amene achita kuti athandize kugwiritsa ntchito CBD ngati mankhwala opha ululu. Kafukufuku wina adayang'ana kugwiritsidwa ntchito kwa CBD pazinthu zake zoteteza thupi m'thupi komanso zotsutsana ndi zotupa. Kafukufuku waku Italiya adachitidwa pazinyama ndipo ofufuza mu kafukufukuyu adayesetsa kukonza ululu wopweteka wamakoswe pogwiritsa ntchito CBD yamlomo. Adapeza kuti 20 mg / kg ya CBD itapatsidwa makoswe okhala ndi ululu wopweteka wopitilira muyeso, makoswe adawonetsa kuchepa kwakukulu kwa zowawa. Mofananamo, adaphunziranso za CBD pakumva kwamitsempha yama makoswe omwe ali ndi kuvulala kwamitsempha yama sciatic ndipo ngakhale imatha kuthetsa ululu, zidapezeka kuti CBD ndiyopindulitsa kwambiri m'maiko osapweteka.

Anthu ambiri amatenga mafuta a CBD kapena opopera kapena mapiritsi a ululu wosatha, ndipo ichi ndi chimodzi mwazifukwa zazikulu zotchuka ndi CBD ndi chamba. Unalinso phindu pakati pa ena ambiri, zomwe zidapangitsa kuti CBD ndi chamba zifalikire zomwe zidapangitsa kuti mankhwala azichotsedwa pamtundu wa CBD pamndandanda wazinthu zomwe zikuyang'aniridwa.

♦ Chithandizo cha khunyu ndi zovuta zina zakukomoka

Khunyu nthawi zambiri imalumikizidwa ndi khunyu koma mavuto ena angapo amatha kubweretsa matenda ngati Dravet Syndrome, Tuberous Sclerosis Syndrome, ndi zina zambiri. Mitundu yoyera yazogulitsa za CBD idaganiziridwa kuti imakhala ndi zotsatira za anti-khunyu kapena anti-khunyu koma panali posachedwapa pomwe panali umboni waukadaulo wa sayansi wotsimikizira izi.

Poyamba, panali mikangano ingapo yokhudzana ndi kugwiritsidwa ntchito kwa CBD makamaka pochiza khunyu ndi zovuta zina zakukomoka. Izi zinali makamaka chifukwa ngakhale CBD ndi anticonvulsant, m'malo ena ovuta, imatha kukhala ngati yovutitsa. Komabe, atayesedwa mosiyanasiyana kawiri kawiri, mayesero azachipatala, zidapezeka kuti sizomwezo. CBD ndi THC onsewa amapezeka kuti ndi anticonvulsants mwachilengedwe.

Zotsatira zamaphunziro angapo, zidapezeka kuti ufa wosalala wa CBD ndi mafuta a hemp a CBD, pakati pazinthu zina za CBD, kukonza ndi kuchiza khunyu koyambitsa khunyu, Dravet Syndrome, Tuberous Sclerosis Syndrome, ndi Lennox-Gastaut Syndrome. Kutsatira izi, a GW Pharmaceuticals adapanga mankhwala okhala ndi CBD concentrate yotchedwa Epidiolex yomwe idalandiranso kuvomerezedwa kwa FDA kuti kugwiritsidwe ntchito ngati mankhwala oletsa kulanda.

Komabe, tiyenera kudziwa kuti sizikudziwikabe ngati zinthu za CBD zomwe zagulidwa kuchokera kwa opanga opanga CBD osiyana ndizothandiza monga Epidiolex pakuthana ndi zizindikilo za matendawa. Izi zili choncho makamaka chifukwa sikuti onse opanga ufa wa CBD komanso ogulitsa ma CBD omwe akupereka ufa ndi zopangidwa za CBD zenizeni koma zopangidwa ndi zowononga zomwe sizingokhala zowunjikira, motero, sizothandiza. Ndikofunikira kwambiri kungogula kuchokera kwa ogulitsa otsimikizika omwe amagulitsa zotsika zapamwamba, zoyera za CBD.

Ofufuza pano akuyesera kuyesa kugwiritsa ntchito CBD ndi THC palimodzi kapena kugwiritsa ntchito CBD kokha pakuwongolera ndikuchiza kugwidwa kwamankhwala, chifukwa kumawopseza moyo wa odwala ndipo nthawi zambiri kumakhala ndi moyo wotsika kwambiri.


♦ Kuchepetsa Nkhawa ndi Kukhumudwa

Kugwiritsa ntchito cannabidiol kwawonetsedwa kuti kumakhala ndi nkhawa komanso kuthana ndi kukhumudwitsa m'mitundu yambiri yazinyama. Pakafukufuku waku Brazil omwe adachitika pa mbewa, zidapezeka kuti CBD ili ndi zovuta zofananira ndi imipramine, anti-depressant yodziwika pa hippocampus ya mbewa zopsinjika. Kafukufukuyu adachitidwa kuti awone zovuta za cannabidiol pamavuto ndikuwunika momwe CBD ingatulutsire zotsatirazi.

Ofufuzawo adapeza kuti CBD imagwiritsa ntchito ma serotonin receptors, makamaka 5HT-1A receptors kuti apange zotsatira zotsutsana ndi kukhumudwitsa kwathunthu. Zinapezekanso kuti, kuti CBD igwire bwino ntchito, kuyambitsa kwa BDNF kapena Brain-derived neurotrophic factor kunali kofunikira.

Komabe, kafukufukuyu adayang'ana kwambiri pazotsatira za CBD pamitundu yazinyama ndipo zotsatira zomwezo sizofunikanso kupangidwa mwa anthu. Ichi ndichifukwa chake kafukufuku adachitika pa amuna 57 athanzi, achikulire kuti awone ngati CBD ili ndi nkhawa komanso yothetsa nkhawa anthu. M'mayeso azachipatala omwe akhungu awiriwa ku Brazil, kugwiritsa ntchito CBD adayesedwa poyerekeza ndi maloboti kuti awunikire zovuta zake ndipo zidapezeka kuti zotsatira za CBD mwa nyama zimatsanzidwanso mwa anthu. Izi zikutanthauza kuti kugwiritsa ntchito CBD kumatha kuchepetsa nkhawa komanso kukhumudwa mwa anthu.

Mafuta a Cannabidiol ndi ufa akukhulupiliranso kuti amathandizira kwambiri pakuthandizira ndikuwongolera zovuta zamankhwala ndi zovuta za PTSD, monga momwe adanenera lipoti lomwe lidasindikizidwa ndi madokotala ku University of Colorado.

Sungani Zizindikiro Zokhudzana ndi Khansa

Chithandizo cha khansa ndi khansa nthawi zambiri chimapereka zisonyezo zosadziwika monga kunyansidwa, kusanza, ndi kupweteka. Zizindikirozi ndizovuta kuzisamalira makamaka chifukwa zimayambiranso ndi chithandizo cha khansa. Komabe, kafukufuku waposachedwa akuwonetsa kuti zizindikiro zokhudzana ndi khansa monga zomwe zatchulidwazi zitha kuyang'aniridwa ndi CBD kapena chisakanizo cha CBD ndi THC.

Kafukufuku wochitidwa ku United Kingdom pa odwala 177 adachitidwa kuti awunikire chitetezo cha CBD ndi THC monga ma nonopioid analgesics mwa odwala omwe ali ndi khansa. Zotsatira zoyambirira za kafukufukuyu zidawonetsa zotsatira zabwino monga odwala ambiri omwe amatenga chisakanizo cha CBD ndi THC akuti kuchepa kwakukulu kwakumva kupweteka, pafupifupi kawiri kuposa gulu la placebo. Izi zikuwonetsa kuthandizira kwama cannabinoids pochiza ndikuwongolera ululu kwa odwala khansa.

Kuphatikiza apo, ofufuza a kafukufuku yemweyo adatsimikiza mtima kupeza njira yothandizirayi yomwe ingachitike kwa odwala khansa popeza chithandizo chambiri cha khansa chimakhala ndi zovuta zina zomwe zimakhudzana nawo. Zinapezeka kuti CBD ndi THC zimaloledwa bwino ndi odwala ndipo kuphatikiza sikunatulutse zovuta zilizonse zomwe ziyenera kutchulidwa.

Chemotherapy ndi mankhwala ofala kwambiri pafupifupi mitundu yonse ya khansa koma siyololedwa bwino ndi thupi la munthu ndipo imatha kuwononga thanzi. Chimodzi mwazovuta zoyipa zomwe zimapezeka pafupifupi kwa odwala onse omwe amalandira chemotherapy ndi chemotherapy-yomwe imayambitsa kusuta ndi kusanza kapena CINV. Ngakhale pali mankhwala angapo a antiemetic, ena mwa iwo makamaka a CINV, sagwira ntchito nthawi zonse. Komabe, kafukufuku yemwe adachitika ku Barcelona adapeza kuti kumwa kwa CBD kumatha kuthandiza kuthana ndi odwala CINV okhala ndi mphamvu zambiri kuposa mankhwala a antiemetic omwe amapangidwira CINV.

Prop Katundu wa Neuroprotective

CBD ili ndi maubwino angapo motsutsana ndi zovuta zama neuropsychiatric pomwe imayang'ana zolandilira zama neurotransmitter osiyanasiyana ndi ma cannabinoid receptors kuti apange zotsatirazi. Mankhwala a CBD, Epidiolex amavomerezedwanso ndi a FDA ndi akuluakulu azaumoyo padziko lonse lapansi kuti athe kuchiza khunyu chifukwa cha khunyu ndi zovuta zina zakomoka.

Potengera maubwino awa, mitundu ingapo ya kafukufuku yachitika kuti aphunzire za CBD pamavuto ena amitsempha, monga Alzheimer's and Multiple Sclerosis.

Kafukufuku yemwe adachitika ku Germany adasanthula zotsatira za Sativex, mankhwala a oro-mucosal CBD pakulimba kwa minofu komwe kumawoneka mwa odwala omwe ali ndi multiple sclerosis. Odwalawa anali ndi vuto losagwirizana ndi mankhwala komanso kupopera kwa CBD, mwa odwalawa, omwe adagwiritsidwa ntchito ngati njira yothandizirana ndi mankhwala omwe analipo kale.

Zinapezeka kuti odwala angapo ofoola ziwalo amalekerera Sativex ndipo sanakumane ndi zovuta chifukwa chodya Sativex. Kuphatikiza apo, ogwiritsa ntchito a Sativex adanenanso za kuchepa kwakukulu kwa mitsempha ya m'mimba ndi kupweteka, zomwe zidapangitsa kuti ofufuzawo alimbikitse kugwiritsa ntchito mafuta a CBD, ufa, ndi kupopera mankhwala kwa odwala omwe ali ndi zopindika za minofu ndi zotuluka chifukwa cha MS.

Kafukufuku wina yemwe adachitidwa kuti aphunzire za CBD pa odwala a Alzheimers awonetsanso zotsatira zabwino, motero kutsimikizira kuti CBD ili ndi zoteteza ku matenda. Pakadali pano, matenda a Alzheimer's ndi osachiritsika a neurodegenerative omwe akakhalapo, sangachedwe kupitilira kapena kusinthidwa konse. Komabe, zotsatira za vitro za CBD pama cell aubongo zimawonetsa chithunzi chatsopano ndipo zimapereka chiyembekezo kwa odwala omwe ali ndi Alzheimer's.

Kupanga lingaliro ili lomwe limapangidwa mu vitro zotsatira za CBD, kafukufuku wachitika pamitundu yazinyama kuti awone ngati Alzheimer's ingasinthidwe ndi nkhanza ndi CBD. Mbewa zokhala ndi zofooka zamaganizidwe ndi gliosis, mawonekedwe a mabala muubongo, chifukwa cha Alzheimer's adapatsidwa CBD ngati gawo la kafukufukuyu. Zinapezeka kuti CBD yachepetsa mabala muubongo ndipo zidapangitsa kuti neurogeneis kapena kukula kwa maselo atsopano aubongo kuti athane ndi kutayika kwa maselo chifukwa cha gliosis yothandizira. Kuphatikiza apo, CBD idapezeka kuti ichepetsa zoperewera zamaganizidwe zomwe zimapezeka mumitundu yamakoswe, ndikupatsa chiyembekezo kuti Alzheimer's itha kusintha ndikuchiritsidwa mtsogolomo.

Ndikofunika kuzindikira kuti zambiri mwazotsatirazi zidapangidwa munyengo yazinyama ndipo zotsatirazi ziyenera kuwerengedwa m'mayesero azachipatala ndi anthu asanayambe kugwiritsa ntchito CBD kukhala mulingo wosamalira.

Management Kusamalira Ziphuphu ndi Chithandizo

CBD yatenga chidwi chifukwa cha analgesic, anxiolytic, ndi anti-inflammatory properties. Ndizo zotsutsana ndi zotupa za izi Nthendayi yomwe yatsogolera ku ntchito yake ngati mankhwala opatsirana ndi ziphuphu. Ziphuphu zimakhulupirira kuti zimachitika chifukwa cha kutupa, mabakiteriya, komanso sebum yambiri. Pakafukufuku wofufuza za mafuta a CBD, zidapezeka kuti CBD imaletsa kutupa motero kukula kwa ziphuphu, zotupa ziphuphu poletsa kutsekemera kwa ma pro-acne cytokines pakhungu. Kuphatikiza apo, kafukufukuyu adapeza kuti CBD imatha kusintha sebum pakhungu poyang'ana kapangidwe kake ndikuchepetsa, mwachindunji.

CBD imagwiritsidwa ntchito pakapangidwe kosamalira khungu kosiyanasiyana komanso ma topical agents omwe amafotokozedwa ngati zotsutsana ndi ziphuphu. Komabe, ndikofunikira kupeza zinthu zomwe zili ndi ukadaulo wothandizira kuti mankhwalawo alowerere pakhungu la munthu. Izi ndikuti zitsimikizire kuti zimalowa pakhungu ndikuchepetsa kutupa kuchokera mkati.

♦ Katundu wa Antipsychotic

CBD imagwiritsidwa ntchito kwambiri potha kuthana ndi zovuta zama neuropsychiatric, ndichifukwa chake mitundu ingapo ya kafukufuku ikuchitika pazotsatira zina za antipsychotic za CBD. Ndipo ambiri mwa maphunzirowa awonetsa kuyankha kwabwino.

Kugwiritsa ntchito mankhwala osokoneza bongo akukhulupirira kuti tsopano kumayambitsa matenda a schizophrenia, matenda osokoneza bongo omwe ali ndi zizindikilo zonga psychosis. Kafukufuku watsopano akuganiza kuti kugwiritsa ntchito CBD kutha kukhala kothandiza pakuthana ndi kuthana ndi psychosis yomwe imawoneka ndi schizophrenia, yomwe imayamba chifukwa chogwiritsa ntchito mankhwala osokoneza bongo, komanso yomwe imayamba chifukwa cha zomwe zimayambitsa chibadwa, osakhudzidwa ndi chamba. Itha kusinthanso matenda amisala omwe nthawi zina amawoneka ndikuwongolera koopsa kwa THC.

Zotsatirazi zikutsimikizira kuti CBD ili ndi ma antipsychotic omwe amafunika kuwunikiridwa chifukwa maubwino awa atha kukhala amtengo wapatali pamankhwala.

♦ Chithandizo ndi kasamalidwe ka Vuto Losokoneza bongo

Matenda osokoneza bongo amapangidwa chifukwa chazomwe zimachitika ndi ma circuits a neuronal, kupangitsa anthu kulakalaka ndikudalira mankhwalawa. M'mabuku omwe ochita kafukufuku adafufuza kuti aone momwe CBD imagwiritsidwira ntchito ngati chithandizo chazovuta zamankhwala osokoneza bongo, zidapezeka kuti CBD imatha kulumikizana ndi ma circonal a neuronal awaletsa, zomwe zimapangitsa kuchepa kwa chidwi ndi kudalira mankhwalawa.

Kuwunikiraku kunaphatikizaponso maphunziro a 14, 9 omwe adachitidwa pazinyama, makamaka mbewa. CBD idapezeka kuti imathandizira kwambiri ma opioid, cocaine, psychostimulant, ndudu, komanso chizolowezi cha khansa. Komabe, izi zinali zoyambirira ndipo zotsatira zina siziyenera kufalitsidwa zotsatira zake zisanalandiridwe konsekonse.

♦ Kupewa matenda ashuga

Matenda ashuga ndi vuto lalikulu lomwe limakhudza gawo lalikulu la anthu padziko lapansi. Kafukufuku waposachedwa wopangidwa pamitundu yazinyama adapeza kuti kugwiritsa ntchito CBD mu mbewa zosaneneka zitha kuchepetsa kwambiri matenda ashuga. Pakafukufukuyu, pakati pamagulu olowererapo ndi gulu la placebo, panali kuchepa kwakukulu kwa matenda ashuga kuchokera pa 86 peresenti mpaka 30 peresenti.

Kuphatikiza apo, kafukufukuyu adapeza kuti kugwiritsidwa ntchito kwa CBD kumatha kubweretsa kuchepa kwa matenda ashuga chifukwa cha zinthu zotsutsana ndi zotupa komanso zoteteza m'mthupi za cannabinoid. Kugwiritsa ntchito kwa CBD munjira zamtunduwu kunathandizanso kuchedwa kuyambitsa insulitis yowononga, imodzi mwanjira zazikulu zomwe zimapangitsa insulin kuchepetsa matenda ashuga.

Kugwiritsa ntchito CBD

CBD ndi malo omwe amapezeka kwambiri omwe amapezeka m'njira zosiyanasiyana kuti ntchito yonse ikhale yosavuta kwa ogwiritsa ntchito. Njira zodziwika bwino zogwiritsira ntchito kapena kugwiritsa ntchito CBD zikuphatikiza, koma sizimangokhala pa:

→ Zokongoletsa za CBD

Othandizira amtunduwu amakhala ndi CBD ndipo amagwiritsidwa ntchito kuthana ndi ululu, kutupa, kutupa, kukwiya pakhungu, ngakhale ziphuphu. Mafuta apakhungu a CBD ayenera kugwiritsidwa ntchito ngati chinthu china chilichonse chosamalira khungu ndikugwiritsa ntchito khungu lomwe limafuna chithandizo.

Mukamagula topicals ndi mafuta a CBD, ndikofunikira kugula mankhwala omwe ali ndi mtundu wina waukadaulo kapena micellization yomwe imalola kuti zosakaniza za wothandizila, monga CBD, zizilowetsedwa ndi khungu ndikuzichitira mkati. Popanda njirazi zotsekemera, ma CBD omwe amakhala ndi ma topical amangokhalira kumtunda osatulutsa phindu lililonse.

→ Vapes a CBD

CBD ikapuma kudzera mu vaping imalola kuti CBD izilowetsedwa mwachangu mthupi, ndikupanga maubwino mwachangu kuposa mtundu wina uliwonse. Popeza imapumidwa m'mapapu kenako imadutsa m'magazi, CBD yomwe ili vape imadutsa kagayidwe koyamba komwe nthawi zambiri kamatenga nthawi yayitali ndikuletsa kuchitapo kanthu mwachangu kwa CBD. Sizili choncho ndi mafunde a CBD ndipo njira iyi yogwiritsa ntchito CBD ndiyodziwika kwambiri pakati pa achinyamata. Ngakhale CBD imagwira ntchito mwachangu ikagwiritsidwa ntchito mwanjira ya vape, imakhalanso ndi kagayidwe kofulumira ndipo imangokhala m'magazi kwa mphindi pafupifupi 10, kutanthauza kuti mphamvu yonse ya mpweya wa CBD imatenga mphindi 10.

Komabe, Dziwani kuti vapes si njira yabwino yogwiritsira ntchito CBD kapena chinthu china chilichonse chotere. Vaping amaonedwa kuti ndiwathanzi kuposa kusuta fodya koma ndiwabwinobe ndipo akuyenera kupewedwa, makamaka chifukwa mitundu ina ya CBD imapezeka mosavuta.

→ Makapisozi a CBD ndi Mapiritsi

Fomu iyi ya CBD ndiyo njira yoyendetsedwa kwambiri ya kudya kwa CBD ndipo imalola ogwiritsa ntchito kudya cannabidiol mu mitundu yosiyanasiyana, kutengera zomwe amakonda komanso zosowa zawo. Mlingo wanthawi zonse wa makapisozi a CBD ndi mapiritsi ali pakati pa 5 mg ndi 25 mg.

→ Maganizo a CBD

CBD imayang'ana, monga momwe dzinalo likusonyezera, imakhala ndi mtundu wokhazikika wa CBD. Pafupipafupi, izi zimabwera ndi zogwiritsa ntchito ndipo zimakhala zowirikiza zana kuposa zopangidwa ndi mitundu ina ya CBD. Ipezeka mu mawonekedwe a ufa, mankhwalawa amayenera kusungidwa mkamwa kwakanthawi asanaumeze kulola kuti CBD izilowetsedwenso mozama komanso kudzera mu metabolism yopititsa patsogolo ikameza.

→ Mafuta a CBD ndi Tinctures

Mafuta a CBD komanso mavitamini amakhalanso ndi CBD yambiri yomwe imayamba 100 mg mpaka 1500 mg. Popeza awa amagwiritsidwanso ntchito pakamwa, ndikofunikira kuwunika kuchuluka kwake ndikupewa kumwa mopitirira muyeso chifukwa izi zitha kuwonjezera ngozi zoyipa ndikuchepetsa zotsatira za CBD.

→ Utsi wa CBD

Fomu iyi ya CBD ndi njira yatsopano yogwiritsira ntchito ndipo, poyerekeza ndi mitundu ina, imakhala ndi CBD yotsika kwambiri. Zomwe zili mu CBD m'mipopera iyi zimakhala za 1 mg mpaka 3 mg pa kutsitsi.

Zotsatira zoyipa za CBD

CBD ndichinthu chotchuka kwambiri chomwe chikugwiritsidwa ntchito kwambiri ndi achinyamata komanso anthu azaka zapakati. Ngakhale zili zowona kuti ufa wa cannabidiol uli ndi maubwino angapo asayansi okhudzana nawo, ndikofunikira kudziwa kuti ndi maubwino awa, pali zovuta zina zoyipa zomwe zimagwiritsidwa ntchito ndi CBD. Zotsatirazi zimawoneka CBD ikamamwa pakamwa, kapena kudzera pakamwa. Kafukufuku wosakwanira wachitidwa kuti adziwe zovuta zomwe zingachitike ndi mitundu yosiyanasiyana yofunsira.

Zotsatira zoyipa za CBD ndi izi:
  • Kuthamanga kwa magazi kapena hypotension
  • Pakamwa pouma kapena Xerostomia
  • Lightheadedness
  • kugona

Zambiri mwa zotsatirazi sizowopsa ndipo zidzathetsedwa zokha. Zogulitsa za CBD zitha kugwiritsidwa ntchito mpaka masabata 13 mosalekeza, ndi mlingo woyenera wa 200mg patsiku, Epidiolex imalumikizidwa ndi kuvulala koopsa kwa chiwindi ngati mutamwa mulingo wambiri momwe mankhwalawo amavomerezedwa kuti agwiritsidwe ntchito pamlingo wambiri kuposa 200mg patsiku , ngakhale ndizovuta kawirikawiri.

Kuyanjana kotheka ndi zidziwitso zapadera za CBD

CBD imaganiziridwa kuti imalekereredwa ndi ambiri mwa akulu ndi achinyamata-achikulire ndipo amatha kupindulitsanso anthuwa. Komabe, ndikofunikira kudziwa kuti pali zodzitetezera zapadera zomwe ziyenera kuchitidwa kwa anthu ena omwe angafune kutenga CBD. Izi ndi za anthu omwe akudwala matenda a chiwindi kapena matenda a Parkinson. Izi zimasintha magwiridwe antchito a zinthu za CBD ndipo chisamaliro chapadera chiyenera kutengedwa ndi odwalawa ngati angasankhe kumwa CBD.

Odwala omwe ali ndi matenda a chiwindi amatha kumwa CBD komabe, adzafunika kumwa mankhwala ochepa a CBD, kuposa munthu wamba chifukwa chiwindi chawo sichitha kupukusa zinthu momwe zimakhalira nthawi zonse. Kafukufuku akuwonetsa kuti kutsika kwa CBD sikukhudza kapena kuyika chiwindi chodwala, kutanthauza kuti odwalawo atha kutenga mankhwala a CBD mosamala.

Odwala omwe ali ndi matenda a Parkinson ali ndi zizindikilo zakupuma kwa kunjenjemera komanso kusunthika kosayenera kwa minofu. Zizindikirozi amakhulupirira kuti zimakokomeza kugwiritsa ntchito mankhwala CBD, ndichifukwa chake odwala a Parkinson akuyenera kupewa kugwiritsa ntchito mankhwalawa.

Zogulitsa za CBD sizilimbikitsidwanso kwa ana, ngakhale sizikudziwika bwinobwino zomwe zingachitike pagululi. Epidiolex, mankhwala omwe amagwiritsidwa ntchito poyang'anira ndikuchiza khunyu, amapatsidwa nthawi zonse kwa ana omwe ali ndi matendawa. Malinga ndi FDA, mankhwalawa ndi otetezeka kugwiritsa ntchito ana koma sadziwika ngati ena mankhwala CBD ali otetezeka kapena ogwira ntchito kwa ana. Kufikira kafukufuku wina atachitika, ndibwino kuti mupewe kupatsa ana zinthu za CBD kupatula Epidiolex.

Amayi apakati ndi amayi omwe akuyamwitsa amafunsidwanso kuti azisamala ndikupewa kugwiritsa ntchito mankhwala a CBD. Komabe, izi sizikachitika makamaka chifukwa cha zotsatira za CBD, zomwe sizikudziwika, koma chifukwa chakutheka kuti mankhwalawa akhoza kuipitsidwa ndi poizoni kapena zinthu zoyipa zomwe zitha kuvulaza mkazi kapena mwana wokula. Popeza sizingatheke kuti aliyense awonetsetse chitetezo cha zinthu zomwe akugwiritsa ntchito, ndibwino kupewa zopangira za CBD panthawiyi.

Kupatula zodzitetezera zapaderazi zomwe zatchulidwa pamwambapa, palibe chomwe chimadziwika pokhudzana ndi momwe mungagwiritsire ntchito mankhwala osokoneza bongo ndi CBD.

Kodi Mitundu Yotani ya CBD Yapangidwa ku AASraw?

AASraw ndi gwero lodalirika la ufa wa steroid, mahomoni ogonana, komanso mankhwala osokoneza bongo. AASraw imakhalanso ndi CBD yopanga komanso yopanga, yopanga zinthu zabwino kwambiri, zotetezeka kugwiritsa ntchito, komanso zogulitsa bwino za CBD. CBD ndichinthu chosunthika chomwe chimapezeka mosiyanasiyana koma si opanga onse omwe amapanga ndikupanga mitundu yonse ya CBD. Fakitole ya CBD imatha kupanga mitundu yosiyanasiyana yazogulitsa, ndipo osati mitundu yonse kuti izitha kuyang'ana kwambiri kutetezedwa kwa malonda.

AASraw ndi wopanga ufa wa CBD ndipo amapanganso Mafuta a CBD, zonsezi ndi zotchuka kwambiri komanso zofunikira kwambiri. Zida zopangidwa ndi AASraw zikuphatikizapo:

→ Ufa wa CBD

CBD Powder kapena concentrate ndi mtundu wa cannabidiol womwe umapangidwa kwambiri ndikugulitsidwa ndi anthu ambiri omwe amayesera kutero Gulani ufa wa CBD chifukwa ndi yosavuta kugwiritsa ntchito komanso yothandiza popanga zotsatira. AASraw ili ndi mtundu winawake wa CBD ufa womwe ungagulitsidwe, womwe umapangidwa mufakitole momwe malangizo azachitetezo amatsata mwatsatanetsatane. Izi zimatsimikizira chitetezo ndi mphamvu ya zinthu, zomwe AASraw, wopanga ufa wa CBD ndi wopereka wa ufa wa CBD, amatsimikizira ndikudzitamandira.

Wopanga ufa wa CBD akuwonetsetsanso kuti zinthuzo sizidetsedwa ndi poizoni kapena zinthu zoyipa panthawi yopanga kapena kupanga phukusi la CBD. Komanso, AASraw ili ndi njira zowongolera zabwino zomwe nthawi zambiri zimakhala zovuta, zimathandizira kutsata ndikukumbukira zinthu zonse zomwe zimapangidwa mgululi.

Mafuta a CBD opangidwa ndi AASraw amatchedwa Powder wosungunuka wa CBD wa Madzi ndipo ndi oyera mpaka ufa woyera womwe uli ndi 10% ya CBD. Chogulitsachi chilibe THC ndipo 90% ina ya ufa imakhala ndi mankhwala ndi zomangira zomwe zimathandizira kukokomeza phindu la CBD ndikulola kuti malonda azikhala limodzi ndikukhalitsa nthawi yayitali.

Mafuta osungunuka amadzimadzi a CBD akuyenera kusakanizidwa ndi madzi kuti apange yankho lamadzimadzi pakafunika kumwa. Yankho lamadzimadzi liyenera kusakanizidwa bwino ndikugwedezeka, zomwe zingapangitse yankho kukhala lavu. Umu ndi momwe mawonekedwe a malonda amakhalira ndipo ndi momwe ziyenera kutengedwa.

Ndikofunika kukumbukira kuti ufa wa CBD uyenera kusungidwa moyenera, kutali ndi dzuwa. Kuphatikiza apo, ufa sangagwirizane ndi asidi kapena m'munsi momwe ungachitire ndi ufa.

→ Mafuta a CBD

Mafuta a CBD, monga tafotokozera pamwambapa, ndi mitundu yamphamvu ya CBD popeza ili ndi CBD poyerekeza mitundu ina. Mafuta a AASraw a CBD onse amapangidwa mu Njira Yabwino Yopangira kapena malo ovomerezeka a GMP, kutsimikizira kuthekera ndi mphamvu kwamafuta a CBD. Mafuta onse a CBD ndi zinthu zina zopangidwa ndi AASraw zimapangidwa kuti zitsimikizire kuti kulibe zonyansa m'zinthu zawo komanso kuti zimakhazikika momwe zingathere.

Pali mitundu iwiri yosiyana ya mafuta a CBD opangidwa ndi AASraw, monga tafotokozera pansipa:

· Hemp N'kofunika Mafuta

Mafuta a CBD Hemp akutchuka chifukwa cha zabwino zambiri za izi, monga tafotokozera pamwambapa. Mafuta ndi otchuka kwambiri kuposa mitundu ina ya zinthu za CBD chifukwa amakhala ndi CBD yambiri.

Hemp Mafuta Ofunika ndi AASraw ndi mafuta owoneka bwino, akuda, komanso achikaso omwe amakhala okhazikika komanso okhazikika. Iyenera kusungidwa kutentha komanso kutalikirana ndi dzuwa kuti zitsimikizire zabwino kwambiri komanso moyo wautali wa malonda. Chogulitsidwa ndi fakitole ya AASraw's CBD ndi gulu lachitatu lomwe limayesedwa ndipo limapezeka m'magulu osiyanasiyana, mwina ndi CBD kapena sipekitiramu yotayidwa cannabinoids.

Chogulitsachi ndi halal, Kosher, ndipo chilibe THC koma chodzaza ndi mankhwala osagwiritsa ntchito mankhwala osokoneza bongo.

· Golden hemp Mafuta

Mafuta a Golden Hemp ndi AASraw ndi gulu lachitatu lomwe lidayesedwa, ndipamwamba kwambiri Nthendayi mafuta omwe ali ndi ma cannabinoids athunthu. Mafuta achikasu achikasu ofiira ndi otuwa omwe amagulitsidwa amagulitsidwa m'matumba osiyanasiyana, ndipo ndizotheka kugula izi mwachindunji kuchokera ku fakitole ya AASraw's CBD makamaka ngati CBD ikufunika kwambiri mu mafuta.

Chogulitsidwacho chimabwera ndi malingaliro apadera posungira popeza kusungira kosayenera kumatha kupangitsa kuti ntchitoyi ikhale yosagwira ntchito. Ndikofunikanso kudziwa kuti ma cannabinoids omwe ali munkhondoyi amatha kulumikizika pakapita nthawi. Izi sizitanthauza kuti mankhwalawa sagwiritsidwenso ntchito koma m'malo mongotenthe mafuta powaika m'madzi osambira amasungunula makhiristo, kulola kuti mafuta azigwiritsidwa ntchito ngati kale.

Momwe Mungasankhire Wopanga Woyenera wa Zogulitsa za CBD?

Opanga angapo a ufa wa CBD amatsimikizira kuti malonda awo ali ndi CBD yoyera, yapamwamba kwambiri koma nthawi zambiri zimakhala zabodza. Ndikofunikira kugula ufa wa CBD kuchokera kwa ogulitsa otsimikizika omwe amatsatira malangizo achitetezo ndikukhala ndi malo oyenera owunikira kuti zitsimikizire chitetezo, mphamvu, ndi mphamvu ya malonda.

Kuphatikiza apo, ndikofunikira kugula ufa wa CBD kuchokera kwa opanga omwe amapereka zinthu zomwe sizimangoyesedwa ndi wopanga ndi ufa wa CBD wokha komanso ndi anthu ena omwe amapitilizabe kutsimikizira kuti chinthu chomaliza chisanatumizidwe kumsika ntchito ndi ogula osiyana. Ngati chinthu chilephera kuyeserera labu lachitatu, chikuyenera kukwiyitsidwa ndi wopanga yemwe amayenera kuwunika chifukwa chake chinthucho chidalephera kuwunika bwino ndipo akuyenera kuthana ndi mavutowo asanapange zatsopano ndikupereka.

Makamaka mukamagula CBD yogulitsa kapena kuyika maoda ochulukirapo a CBD, ndikofunikira kuti mufufuze bwino za malonda ndi wopanga kuti apewe zovuta zilizonse zomwe zingapezeke zotsalira. Ngati phindu lalikulu la CBD likufunika, kufunsa kwina kwa wopanga kuyenera kuchitidwa kuti zitsimikizire kuti chinthu chomwe munthu agula chimakhala chambiri mu CBD, ndipo CBD yokha. Chogulitsacho sichiyenera kukhala ndi THC kapena zina cannabinoids zomwe zimachepetsa zovuta za CBD kapena kuletsa kuti zizigwira ntchito mokwanira.

Tsamba:

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