Lorcaserin HCL ufa (1431697-94-7) hplc≥99% | Kuwonetsa Kutayika kwa Mafuta
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Lorcaserin HCL ufa

mlingo: SKU: 1431697-94-7. Category:

AASraw ili ndi kaphatikizidwe ndi kupanga kupanga kuchokera ku gramu mpaka kulemera kwa Lorcaserin HCL powder (1431697-94-7), pansi pa malamulo a CGMP ndi dongosolo loyendetsa khalidwe labwino.

Lorcaserin (1431697-94-7) HCL ufa zimakhudza zizindikiro zamagulu mu ubongo zomwe zimadzetsa chilakolako. Mankhwala a Lorcaserin HCL amagwira ntchito mwa kukuthandizani kuti mukhale odzaza ndi zakudya zing'onozing'ono.Corcaserin hydrochloride powder imagwiritsidwa ntchito pamodzi ndi zakudya ndi masewera olimbitsa thupi kuti muchepetse kunenepa kwambiri. Nthawi zina amagwiritsidwa ntchito pofuna kuchiza kunenepa komwe kumakhudzana ndi shuga, cholesterol, kapena kuthamanga kwa magazi .

Mafotokozedwe Akatundu

 

Lorcaserin (1431697-94-7) kanema

 

 


 

Kuwopsa kwa Lorcaserin (1431697-94-7) HCL powder

 

Name: Lorcaserin hydrochloride ufa
CAS: 1431697-94-7
Maselo chilinganizo: C11H15Cl2N
Kulemera kwa Maselo: 232.1525
Melt Point: 212 ° C
Kusungirako nyengo: -20 ℃
mtundu; White powder

 


 

Lorcaserin ndi chiyani?

 

Lorcaserin (CAS 1431697-94-7), yogulitsidwa pansi pa dzina lake ndi BELVIQ, chinthu chachikulu ndi Lorcaserin HCL poda 846589-98-8. A FDA amavomereza HCL kwa anthu omwe ali ochepa kwambiri (omwe ali ndi chiwerengero cha thupi, kapena BMI, a 30 kapena apamwamba) kapena omwe ali olemera kwambiri (omwe ali ndi BMI ya 27 kapena pamwambapa) komanso amakhala ndi thanzi labwino lofanana ndi lolemera. monga mtundu wa 2 shuga, kuthamanga kwa magazi kapena cholesterol.

 

Kodi Lorcaserin amagwiritsira ntchito chiyani?

 

Kalcaserin HCL ufa 846589-98-8, ali m'kalasi la mankhwala omwe amatchedwa serotonin receptor agonists. Lorcaserin HCL imagwiritsidwa ntchito limodzi ndi zakudya ndi zomanga thupi kuti muzitha kunenepa kwambiri, chifukwa cha kutayika kwa mafuta. Nthaŵi zina amapatsidwa kuti azitha kunenepa kwambiri ndi cholesterol, kuthamanga kwa magazi, kapena matenda a shuga a type2. Koma Lorcaserin hydrochloride (Lorcaserin HCL) sangasamalire matenda aliwonse (monga matenda a mtima, shuga, kuthamanga kwa magazi).

 

Lorcaserin njira yogwirira ntchito

 

Lorcaserin hydrochloride powder amagwira ntchito poletsa chilakolako - makamaka poyambitsa ubongo wa seroton, serotonin, neurotransmitter yomwe imayambitsa chisangalalo cha kukhutira ndi kukhutira. Kudya kwa chakudya kumayang'aniridwa ndi malo osungirako zinthu, omwe ali pamtundu wa phokoso la hypothalamus ndi njala yomwe ilipo potsatira phokoso la hypothalamus. Zipangizo zosiyanasiyana zochokera m'mapiritsi apamwamba ndi m'mimba zimatuluka pamtunda, pomwe pali mitundu iŵiri ya neuroni yomwe ikulamulira chakudya. Choyamba, gulu lothandizira zakudya zomwe zimapanga mapuloteni okhudzana ndi agouti ndi neuropeptide Y; ndipo kachiwiri, gulu lokhala ndi chakudya chokhala ndi cocaine ndi amphetamine (MAP) ndi pro-opiomelanocortin (POMC) neurons. POMC ili ndi mapuloteni a 5-HT 2C, omwe amamasulidwa kutulutsa makina a alpha-melanocyte-stimulating hormone (al-MSH) .Zomwezi zimapangitsa kuti pulojekiti ikhale yopanda mphamvu mu hypothalamus.Paventricular nucleus imakhala ndi melanocyte 4 receptors (MC4R) yomwe imaletsa chilakolako. Mankhwalawa amachititsa 5-HT 2C agonist pa POMC neurons, zomwe zimapangitsa kuti MSH alandidwe. Palinso alfa MSH amagwira MC4R mu nthenda yowonongeka mu hypothalamus, zomwe zimapangitsa kuchepa kwa njala. Mu mankhwala a supratherapeutic, lorcaserin imagwiranso ntchito pa 5-HT 2B ndi 5-HT 2A receptors.

 

Momwe mungagwiritsire ntchito ufa wa Lorcaserin HCL (CAS 1431697-94-7)

 

Ufa wa Lorcaserin HCL ndi ufa wonyezimira wonyezimira wosungunuka m'madzi opitilira 400 mg / mL. Tebuleti iliyonse ya BELVIQ XR imakhala ndi 20.8 mg wa crystalline lorcaserin hydrochloride hemihydrate, wofanana ndi 20.0 mg lorcaserin hydrochloride powder, ndi zotsatirazi zosagwira ntchito: microcrystalline cellulose NF; mannitol USP; hypromellose 2208 USP; kufalikira kwa ethylcellulose Mtundu B NF; hypromellose 2910 USP; colloidal pakachitsulo woipa NF; polyvinyl mowa USP; polyethylene glycol NF; titaniyamu woipa USP; talc USP; FD & C wachikasu # 6 / kulowa dzuwa chikasu FCF; zotayidwa nyanja; chitsulo okusayidi chikasu NF; chitsulo chosayidi chofiira NF; ndi magnesium stearate NF.

Lorcaserin HCL ufa 846589-98-8 imabwera mu mawonekedwe apiritsi ndipo imatengedwa nthawi zambiri 1-2 pa tsiku, kapena popanda chakudya. Lorcaserin iyenera kugwiritsidwa ntchito limodzi ndi zakudya zochepa zowonjezera kalori komanso ndondomeko yochita masewera olimbitsa thupi.

 

Lorcaserin Kuyankhulana

 

-monoamine oxidase inhibitors monga isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), selegiline (Emsam, Eldepryl, Zelapar), rasagiline (Azilect)

-sective serotonin reuptake inhibitors (SSRIs) monga escitalopram (Lexapro), sertraline (Zoloft), citalopram (Celexa), paroxetine (Paxil), fluoxetine (Prozac, Sarafem), ndi fluvoxamine (Luvox)

-tricyclic antidepressants monga trimipramine (Surmontil), amitriptyline (Elavil), nortriptyline (Pamelor, Aventyl), protriptyline (Vivactil), ndi clomipramine (Anafranil)

 


 

Mungagule bwanji ufa wa Lorcaserin HCL (CAS 1431697-94-7) kuchokera ku AASraw

 

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