Urolithin A (1143-70-0) ufa - Wopanga Mafakitale Wopanga
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Urolithin A.

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Urolithin A ndi metabolite yachiwiri ya ellagic acid, polyphenolic antioxidant, yomwe imakhala ndi antiproliferative, anti-inflammatory, and anti-oxidant.
Odziwika: Urolithin A 8-Methyl Ether (CAS: 35233-17-1) ndi wapakatikati pakuphatikizika kwa Urolithin A, metabolite yayikulu ya Ellagitannin ndikuwonetsa zotsutsana ndi zotupa komanso antioxidant.

Mafotokozedwe Akatundu

Makhalidwe Abwino

Name mankhwala Urolithin A.
Nambala ya CAS 1143-70-0
Molecular Formula C13H8O4
Kulemera kwa Fomu 228.2
Mafananidwe 2 ′, 7-Dihydroxy-3,4-benzocoumarin

3,8-Dihydroxy Urolithin;

Urolithin A 8-Methyl Etere;

3-Hydroxy-8-methoxy-6H-dibenzo [b, d] pyran-6-imodzi.

Maonekedwe White crystalline powder
Kusungirako ndi Kusamalira Youma, mdima ndi 0 - 4 C kwakanthawi kochepa (masiku mpaka masabata) kapena -20 C kwakanthawi (miyezi mpaka zaka).

 

Reference

[1] Wopereka ndalama, S. et al. Kuchotsa kwa DNA kwa mitochondrial m'maselo amtundu wa satellite: tanthauzo la mankhwala. Hum. Mol. Chibadwa. 22, 4739-4747 (2013)

[2] Bialonska D, Kasimsetty SG, Khan SI, Ferreira D (11 Novembala 2009). "Urolithins, m'mimba ma microbial metabolites a Pomegranate ellagitannins, amawonetsa mphamvu ya antioxidant pazochita zoyeserera". J Agric Chakudya Chem. 57 (21): 10181-6. onetsani: 10.1021 / jf9025794. MAFUNSO: PMID 19824638.

[3] Milburn, MV & Lawton, KA Kugwiritsa ntchito metabolomics kuti mupeze vuto la insulin. Annu. Rev. Med. 64, 291-305 (2013).

[4] Cerdá, Begoña; Tomás-Barberán, Francisco A .; Espín, Juan Carlos (2005). "Metabolism of Antioxidant and Chemopreventive Ellagitannins ochokera ku Strawberries, Raspberries, Walnuts, ndi Vinyo Wakale Wakale Mwa Anthu: Kuzindikiritsa Kwa Biomarkers ndi Kusintha Kwawo Aliyense". Zolemba pa Zaulimi ndi Chakudya Chemistry. 53 (2): 227-235. onetsani: 10.1021 / jf049144d. PMID 15656654.

[5] Laker, RC neri Al. Phosphorylation ya Ampk ya Ulk1 imafunikira pakukakamiza mitochondria kupita ku lysosomes mu mitophagy yolimbitsa thupi. Nat. Commun. 8, 548 (2017).