Mafotokozedwe Akatundu
Makhalidwe Abwino
| Name mankhwala | Urolithin A. |
| Nambala ya CAS | 1143-70-0 |
| Molecular Formula | C13H8O4 |
| Kulemera kwa Fomu | 228.2 |
| Mafananidwe | 2 ′, 7-Dihydroxy-3,4-benzocoumarin 3,8-Dihydroxy Urolithin; Urolithin A 8-Methyl Etere; 3-Hydroxy-8-methoxy-6H-dibenzo [b, d] pyran-6-imodzi. |
| Maonekedwe | White crystalline powder |
| Kusungirako ndi Kusamalira | Youma, mdima ndi 0 - 4 C kwakanthawi kochepa (masiku mpaka masabata) kapena -20 C kwakanthawi (miyezi mpaka zaka). |
Urolithin A ufa (1143-70-0) -COA
Urolithin A ufa (1143-70-0) -COA
Wolemba nkhaniyi:
Dr. Monique Hong adamaliza maphunziro awo ku UK Imperial College London Faculty of Medicine
Scientific Journal paper Wolemba:
1. CC Carson
Dipatimenti ya Opaleshoni, Division of Urology, University of North Carolina, Chapel Hill, NC,
2. I. Eardley
Chipatala cha St. James' University, Leeds, UK,
3. DJ Walker
Eli Lilly and Company, Indianapolis, IN, USA
4. WH Cordell
Eli Lilly and Company, Indianapolis, IN, USA
Dokotala/wasayansiyu savomereza kapena kulimbikitsa kugula, kugulitsa, kapena kugwiritsa ntchito mankhwalawa pazifukwa zilizonse. Aasraw alibe chiyanjano kapena ubale, wonenedwa kapena ayi, ndi dokotala uyu. Cholinga chotchula dokotalayu ndikuvomereza, kuvomereza ndi kuyamika ntchito yofufuza ndi chitukuko yomwe asayansi akugwira ntchitoyi.
Reference
[1] Wopereka ndalama, S. et al. Kuchotsa kwa DNA kwa mitochondrial m'maselo amtundu wa satellite: tanthauzo la mankhwala. Hum. Mol. Chibadwa. 22, 4739-4747 (2013)
[2] Bialonska D, Kasimsetty SG, Khan SI, Ferreira D (11 Novembala 2009). "Urolithins, m'mimba ma microbial metabolites a Pomegranate ellagitannins, amawonetsa mphamvu ya antioxidant pazochita zoyeserera". J Agric Chakudya Chem. 57 (21): 10181-6. onetsani: 10.1021 / jf9025794. MAFUNSO: PMID 19824638.
[3] Milburn, MV & Lawton, KA Kugwiritsa ntchito metabolomics kuti mupeze vuto la insulin. Annu. Rev. Med. 64, 291-305 (2013).
[4] Cerdá, Begoña; Tomás-Barberán, Francisco A .; Espín, Juan Carlos (2005). "Metabolism of Antioxidant and Chemopreventive Ellagitannins ochokera ku Strawberries, Raspberries, Walnuts, ndi Vinyo Wakale Wakale Mwa Anthu: Kuzindikiritsa Kwa Biomarkers ndi Kusintha Kwawo Aliyense". Zolemba pa Zaulimi ndi Chakudya Chemistry. 53 (2): 227-235. onetsani: 10.1021 / jf049144d. PMID 15656654.
[5] Laker, RC neri Al. Phosphorylation ya Ampk ya Ulk1 imafunikira pakukakamiza mitochondria kupita ku lysosomes mu mitophagy yolimbitsa thupi. Nat. Commun. 8, 548 (2017).
